Hi Ron, and thank you!!  That is great information, and I will share with my doctor. 



Regards!  

Trish



-----Original Message-----

From:         Ron Hoggan <[log in to unmask]>

Sender:       Paleolithic Eating Support List <[log in to unmask]>

Date:         Fri, 24 Sep 2010 18:39:44 

To: <[log in to unmask]>

Reply-To:     Paleolithic Eating Support List <[log in to unmask]>

Subject: Re: Ketoacidosis - diabetic



  Hi Trish,

As a type II diabetic you have little risk of developing ketoacidosis. 

Here is a direct quote from a paper by Anssi H. Manninen that appeared 

in Journal of the International Society of Sports Nutrition. 1(2):7-11, 

2004. (www.sportsnutritionsociety.org) under the title "METABOLIC 

EFFECTS OF THE VERY-LOW-CARBOHYDRATE DIETS: MISUNDERSTOOD “VILLAINS” OF 

HUMAN METABOLISM"





DIABETIC KETOACIDOSIS VS. DIETARY KETOSIS

Diabetic patients know that the detection in their urine of the ketone 

bodies is a danger signal that their diabetes is poorly controlled. 

Indeed, in severely uncontrolled diabetes, if the ketone bodies are 

produced in massive supranormal quantities, they are associated with 

ketoacidosis. In this life-threatening complication of diabetes 

mellitus, the acids 3-hydroxybutyric acid and acetoacetic acid are 

produced rapidly, causing high concentrations of protons, which 

overwhelm the body’s acid-base buffering system. However, during very 

low carbohydrate intake, the regulated and controlled production of 

ketone bodies causes a harmless physiological state known as dietary 

ketosis. In ketosis, the blood pH remains buffered within normal limits. 

Ketone bodies have effects on insulin and glucagon secretions that 

potentially contribute to the control of the rate of their own formation 

because of antilipolytic and lipolytic hormones, respectively. Ketones 

also have a direct inhibitory effect on lipolysis in adipose tissue. 

Interestingly, the effects of ketone body metabolism suggest that mild 

ketosis may offer therapeutic potential in a variety of different common 

and rare disease states . The large categories of disease for which 

ketones may have therapeutic effects are: 1) diseases of substrate 

insufficiency or insulin resistance; 2) diseases resulting from free 

radical damage; and 3) disease resulting from hypoxia.



This is an unfortunate myth that has its roots in many medical students 

being taught that the terms ketosis and ketoacidosis are the same thing.



I hope that helps.

best wishes,

Ron





-- 

PK