Wondering if anyone on the list is using fasting vs. caloric restriction?  Isn't fasting paleo?

Kath 


 8) ABSTRACT: Weight-Cycling Decreases Incidence and Increases Latency
    of Mammary Tumors to a Greater Extent Than Does Chronic Caloric
    Restriction in Mouse Mammary Tumor Virus- Transforming Growth
    Factor-{alpha} Female Mice
    [09/11/2002; Cancer Epidemiology, Biomarkers and Prevention]

Multiple periods of caloric restriction (or fasting)/refeeding
in rodents have had inconsistent effects on mammary tumor (MT)
development. In the present study, the consequence of intermittent
caloric restriction/refeeding resulting in weight-cycling was
evaluated using an oncogene-induced MT mouse model. Hybrid mouse
MT virus-transforming growth factor alpha (MMTV-TGF-alpha)/Lep^+Lep^ob 
female mice were used. Ad libitum-fed mice (n = 30) were fed American
Institute of Nutrition (AIN)-93M diet. Beginning at 10 weeks
of age, weight-cycled mice (n = 30) were fed an AIN-93 modified
diet (2-fold increase in protein, fat, vitamin, and mineral contents)
at 50% of ad libitum for 3-week intervals followed by 3-week
intervals of ad libitum feeding using AIN-93M diet. Pair-fed
mice (n = 33), were fed a 2:1 mixture of AIN-93M:AIN-93 modified
diets to match the caloric intake of weight-cycled mice for each
6-week age-matched caloric restriction/refeeding interval. Food
intakes were determined daily and body weights weekly. Mice were
euthanized when MTs exceeded 20 mm in length or at 80 weeks of
age. Final body weights were similar, but cumulative food intake
of ad libitum-fed mice was 21% greater than that of the other
groups. Ad libitum-fed mice had a 77% MT incidence versus 3%
for weight-cycled and 44% for pair-fed mice. MTs were detected
earlier for ad libitum-fed mice, 64.1 weeks versus 73.5 weeks
for pair-fed mice. The only MT in one weight-cycled mouse was
excised at necropsy (80 weeks of age) and weighed only 0.063
g. Average MT weight for ad libitum-fed mice was 1.034 g and
for pair-fed mice was 0.667 g. Intervals of caloric restriction/refeeding
resulting in weight-cycling were protective against MT development
in this mouse model. Future studies should address the application
of this intervention to additional transgenic mice as well as
other MT models. 

The full article can be found at:

http://cebp.aacrjournals.org/cgi/content/abstract/11/9/836