CELIAC Archives

Celiac/Coeliac Wheat/Gluten-Free List

CELIAC@LISTSERV.ICORS.ORG

Options: Use Forum View

Use Monospaced Font
Show Text Part by Default
Show All Mail Headers

Message: [<< First] [< Prev] [Next >] [Last >>]
Topic: [<< First] [< Prev] [Next >] [Last >>]
Author: [<< First] [< Prev] [Next >] [Last >>]

Print Reply
Subject:
From:
Heidi Schuppenhauer <[log in to unmask]>
Reply To:
Heidi Schuppenhauer <[log in to unmask]>
Date:
Sat, 28 Jun 2003 12:56:27 -0700
Content-Type:
text/plain
Parts/Attachments:
text/plain (36 lines)
<<Disclaimer: Verify this information before applying it to your situation.>>

This is extremely significant, I think!

This might explain a lot of these "unexplained" gluten reactions, and
refractive celiac disease. A lot of foods cause a candida overgrowth, and
if the protein strings are the same, then your body would react to candida
as it would to gluten. Can anyone out there with a science background
comment on that?

--------------
Is Candida albicans a trigger in the onset of coeliac disease?

Nieuwenhuizen WF, Pieters R, Knippels L, Jansen M, Koppelman SJ.
Netherlands Organisation for Applied Scientific Research (TNO) Nutrition
and Food Research, PO Box 360, 3700 AJ, Zeist, Netherlands

Coeliac disease is a T-cell-mediated autoimmune disease of the small
intestine that is induced by ingestion of gluten proteins from wheat,
barley, or rye. We postulate that Candida albicans is a trigger in the
onset of coeliac disease. The virulence factor of C albicans-hyphal wall
protein 1 (HWP1)-contains aminoacid sequences that are identical or highly
homologous to known coeliac disease-related alpha-gliadin and gamma-gliadin
T-cell epitopes.

HWP1 is a transglutaminase substrate, and is used by C
albicans to adhere to the intestinal epithelium. Furthermore, tissue
transglutaminase and endomysium components could become covalently linked
to the yeast. Subsequently, C albicans might function as an adjuvant that
stimulates antibody formation against HWP1 and gluten, and formation of
autoreactive antibodies against tissue transglutaminase and endomysium.

-- Heidi

*Support summarization of posts, reply to the SENDER not the CELIAC List*

ATOM RSS1 RSS2