<<Disclaimer: Verify this information before applying it to your situation.>>

Finally, my summary on biopsy.  My original question was .  ...  When
someone has been given blood tests (1 positive and 1 negative), then is
given a biopsy which is negative, does that mean that person does not
have Celiac Disease and never will?  Or does that mean that at this
time there has not been a trigger and CD has not yet shown up but could
later in life??

The very best advise was to contact Dr. Cynthia Rudert who is a Celiac
expert through the Clan Thompson web site.

Go to this web site: http://www.idsl.net/celiac/

E-mail Clan Thompson (it is a celiac family of 4) and ask how you can get
that answered by Dr. Rudert.

My reply from Dr. Rudert was:
Unfortunately I would like to have a little more information to
completely answer this question.  I would like to know if the blood
tests were positive, specifically, the anti-endomysial antibody,
tissue transglutaminase or anti-gliadin antibody.  Occasionally
individuals may have "latent" Celiac disease and therefore normal
biopsies could theoretically eventually become abnormal in
genetically predisposed individuals if certain triggers occur.  Also, if
the biopsies were not obtained from the correct locations this could
represent a false negative due to sampling error.  In other words, if
you don't biopsy in the location with the highest yield, you may
miss the disease and if only one biopsy was obtained, I feel this is
inadequate.  It is my personal bias to take anywhere from 12 to 20
biopsies from the duodenum/jejunum.

Other responses are:

This just happened to me.  I received negative results from the biopsy
day before yesterday.  I feel absolutely better off wheat as well as milk
and maybe soy.  Please let me know what you found out.  I had a strong
positive to the IgA test and negative to the IgA test.

If the positive blood test was the antigliadin antibody IgG, and the
negative was the IgA, and the biopsy was negative, this means they don't
have Celiac now, but if they have inherited the genes, they could develop
it down the road.

I would like to relate my experience regarding having my son tested
genetically to determine if he had the potential to develop Celiac
disease in the future.

What helped me the most with reaching this goal was an ad in Ann Whelan's
Gluten Free Newsletter for Specialty Laboratories in California and they
had the Celiac Disease GenotypR test (#1078) listed.  In addition they
had the Celiac Disease EvaluatR (#1077) which includes Transglutaminase
IgA autoantibodies, IgG & IgA gliadin antibodies, IgA endomysial
autoantibodies, and IgA reticulin autoantibodies.


If anyone finds other info on the subject, please keep us all informed!!

Thanks for all of the great help,
Krista