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Subject:
From:
John Dennis <[log in to unmask]>
Date:
Thu, 18 May 1995 09:04:17 -0400
Content-Type:
text/plain
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<<Disclaimer:  Verify this information before applying it to your situation.>>

 James Lyles <[log in to unmask] wrote on 17 May concerning someone
experiencing "neurological problems:  unsteady gait, weakness of hands and
limbs, and muscle spasms."

The following abstract from Medline may be relevant:

MEDLINE(R) (c) format only 1995 Knight-Ridder Info. All rts. reserv.
09277252   95207252
[Celiac disease in adults revealed by sensory-motor neuropathy]
Maladie coeliaque de l'adulte revelee par une neuropathie sensitivo-motrice.
Viader F; Chapon F; Dao T; Rivrain Y; Lechevalier B
Service de Neurologie, CHRU de Caen.
Presse Med (FRANCE)   Jan 28 1995,  24 (4) p222-4,  ISSN 0755-4982
Journal Code: PMT
Languages: FRENCH   Summary Languages: ENGLISH
Document type: JOURNAL ARTICLE   English Abstract
JOURNAL ANNOUNCEMENT: 9506
Subfile:   INDEX MEDICUS

Central  or  peripheral  nervous  system  complications  are occasionally
observed  in  adult  patients  with celiac disease. Several mechanisms have
been  proposed  including  vitamin  deficiency, vascular inflammation and a
direct  effect  of  gluten  intolerance.  Typical nerve fiber damage due to
demyelinization  has been suggested. We observed a 65-year old woman with a
right  peroneal nerve palsy superimposed on a diffuse peripheral neuropathy
who  was  found  to  have  folic  acid  deficiency which in turn led to the
diagnosis  of  adult  celiac disease. Electrophysiological and histological
studies  demonstrated  a  predominantly demyelinating peripheral neuropathy
which  responded  first to parenteral folic acid supplementation and second
to  a  gluten-free diet. The mechanisms of peripheral nerve damage in adult
celiac  disease  are  briefly discussed and the possible role of folic acid
deficiency is emphasized.

Tags: Case Report; Female; Human

Descriptors:*Celiac  Disease--Complications--CO;  *Peripheral  Nervous
System   Diseases--Etiology--ET;   Aged;   Celiac   Disease--Diagnosis--DI;
Demyelinating   Diseases--Etiology--ET;   Electrophysiology;   Folic   Acid
Deficiency--Complications--CO

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