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From:
L and N Matsui <[log in to unmask]>
Date:
Sat, 16 Feb 2002 18:02:12 -0500
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<<Disclaimer: Verify this information before applying it to your situation.>>

According to Gastroenterology 2001 (vol. 120, no. 3) by Fasano and Catassi,
The asymptomatic (Silent) form  "is characterized by the presence of
histologic changes, probably limited to the proximal intestine, that occur
in individuals who are apparently asymptomatic.  Most of the cases in this
category have been identified through screening programs involving
apparently healthy subjects.  However, a more careful clinical anamnesis
typically reveals that many of these "'silent'" cases are indeed affected by
low-intensity illness often associated with decreased psychophysical
well-being.  Common findings include (1) iron deficiency with or without
anemia; (2) behavioral disturbances, such as tendency to depression,
irritability, or impaired school performance in children; (3) impaired
physical fitness, "'feeling always tired,'" and easy fatigue during
exercise; and (4) reduced bone mineral density.  A 24-month follow-up study
showed that adolescents with screening-detected CD who were apparently
symptomless at diagnosis often reported improved physical and psychologic
conditions once they began following a GFD.  The most common changes
included increased weight and height velocity, increased appetite, mood
amelioration,and improved physical and school performance.  Finally, current
evidence suggests that subjects with "'silent'" CD are at risk to develop
the same long-term complications experienced by individuals with typical
symptoms."

P.S. TJ Campbell, I hope this answers your Q.

Laura

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