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Subject:
From:
Charlotte Ward-Perkins <[log in to unmask]>
Reply To:
Charlotte Ward-Perkins <[log in to unmask]>
Date:
Tue, 14 Dec 2004 11:19:41 -0000
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<<Disclaimer: Verify this information before applying it to your situation.>>

Coeliacs often report changes in bowel habits after going on the diet and worry about additional lactose intolerance etc... This article may help reassure people that some changes happen spontaneously (NB the full text - which is no doubt riveting reading - is only available to subscribers).
Charlotte, Oxford, UK
Gut transit in celiac disease: delay of small bowel transit and acceleration after dietary treatment.
Am J Gastroenterol. 2004 Dec;99(12):2429-36. Sadik R, Abrahamsson H, Kilander A, Stotzer PO.
Section of Gastroenterology, Institute of Internal Medicine, Sahlgrenska University Hospital, University of Goteborg, Goteborg, Sweden. "OBJECTIVES: New studies indicate that body mass index (BMI) may influence gut transit. We studied gut transit and BMI in patients with celiac disease before and after treatment. METHODS: Twenty-seven (16 female) patients with untreated celiac disease were included for detailed gastrointestinal transit measurement and calculation of BMI. Ten patients (5 female) were also studied after dietary treatment. A newly developed radiological transit procedure was used. Eighty-three healthy subjects were used as controls. RESULTS: In untreated male patients BMI was significantly reduced compared to healthy males, and small bowel transit time (SBTT) was significantly longer compared with healthy males, 3.9 (1.2-5.5) versus 2.5 h (1.4-4.3), median and percentile 10 and 90, respectively, and p= 0.04. In the 10 men and women with repeated measurements, BMI increased significantly and small bowel transit accelerated after treatment and was 3.6 h (1.7-5.5) before treatment and 2.3 h (0.7-4.0) after treatment, and p= 0.007. In women, BMI did not differ significantly between untreated patients and healthy subjects, and 31% of the female patients were overweight. Small bowel transit was significantly faster in untreated female patients who were overweight compared with lean female patients. CONCLUSION: Small bowel transit seems to be delayed in lean patients with untreated celiac disease. BMI may have some influence on the variations of small bowel transit before and after treatment." 
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15571592

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