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Hello List Mates,
I found the results of this study interesting and thought you might too:
Comments? I'll summarize.
Thanks,
Deb Wheaton
www.notevenacrumb.com
"Raising Awareness, One Crumb at a Time"

A study in this month's issue of Gastrointestinal Endoscopy investigates capsule endoscopy in nonresponsive celiac disease.
Nonresponsive celiac disease is defined by persistent or recurrent symptoms, common after treatment with a gluten-free diet.
Dr David Atlas and colleagues evaluated the utility of capsule endoscopy in nonresponsive celiac disease.
The team identified 42 consecutive patients with nonresponsive celiac disease, and 84 age- and sex-matched celiac disease-free controls who underwent capsule endoscopy were included. 
 
Villous atrophy was detected in 31% with nonresponsive celiac disease 
Gastrointestinal Endoscopy
In addition, capsules taken after treatment with a gluten-free diet were retrospectively evaluated in 30 patients with uncomplicated celiac disease.
The team's main outcome measurements included the diagnostic accuracy of capsule endoscopy for the detection of mucosal abnormalities in nonresponsive celiac disease.
Macroscopic features of villous atrophy were detected in 31% of patients with nonresponsive celiac disease compared with none among 84 celiac disease-free controls, and 47% of patients with uncomplicated celiac disease. 
The team found that among nonresponsive celiac disease cases, the overall sensitivity and specificity of capsule endoscopy for the detection of any degree of villous atrophy as graded by histology were 56% and 85%, respectively. 
The research team observed single or multiple erosions/ulcerations of the gut in 19% of nonresponsive celiac disease patients, 18% of celiac disease-free controls, and 31% of patients with uncomplicated celiac disease. 
The team noted that the presence of erosions/ulcerations was associated with increased aspirin/nonsteroidal anti-inflammatory drug use in nonresponsive celiac disease. 
The research team detected 2 severe complications by capsule endoscopy in nonresponsive celiac disease.
Dr Atlas' team commented, "Mucosal abnormalities were observed by capsule endoscopy in patients with both nonresponsive celiac disease and uncomplicated celiac disease."
"Capsule endoscopy can detect severe complications in patients with nonresponsive celiac disease."

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