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Babies of Pregnant Women with CD at Higher Risk of Low Birth Weights


According to a study published in the American Gastroenterological Association’s publication, “Gastroenterology”, pregnant women are at a higher risk of having smaller fetuses and babies with low birth weights when they have elevated levels of the antibodies* associated with Celiac Disease.

*Note: The antibody known as Tissue Transglutaminase (anti-tTG) is most commonly found in patients with Celiac Disease.

“While several observational studies have suggested that Celiac Disease is associated with different pregnancy outcomes, this research takes into account the actual levels of tTG that reflect the degree of mucosal damage associated with undiagnosed Celiac Disease or limited compliance to a gluten-free diet. This differentiation is critical since most Celiac Disease cases remain undiagnosed," said Jessica Kiefte-de Jong, MSc, Erasmus University Medical Center, and lead author of the study.

The study involved over 7000 pregnant women separated into three groups: 

* Negative anti-tTG pregnant women

* Intermediate anti-tTG (just below the clinical cut-off point used to diagnose patients with Celiac Disease).

* Positive anti-tTG (highly probable Celiac Disease patients). 

Fetuses of women with positive anti-tTG weighed 16 grams less than those of women with negative anti-tTG levels during the 2nd trimester and weighed 74 grams less during the 3rd trimester.

People with intermediate anti-tTG levels, who are generally not considered to be potential Celiac Disease patients, had births that were also impacted.  Infants of women with intermediate and positive anti-tTG weighed 159 grams less at birth compared to pregnant women with negative anti-tTG.
 
To learn more about this study or to have you very own at-home screening for Celiac Disease and Food Intolerance, please contact Better Control of Health at www.bettercontrolofhealth.com.

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