CELIAC Archives

Celiac/Coeliac Wheat/Gluten-Free List

CELIAC@LISTSERV.ICORS.ORG

Options: Use Forum View

Use Monospaced Font
Show Text Part by Default
Show All Mail Headers

Message: [<< First] [< Prev] [Next >] [Last >>]
Topic: [<< First] [< Prev] [Next >] [Last >>]
Author: [<< First] [< Prev] [Next >] [Last >>]

Print Reply
Subject:
From:
Charlotte Ward-Perkins <[log in to unmask]>
Reply To:
Charlotte Ward-Perkins <[log in to unmask]>
Date:
Fri, 6 Feb 2004 17:31:24 -0000
Content-Type:
text/plain
Parts/Attachments:
text/plain (12 lines)
<<Disclaimer: Verify this information before applying it to your situation.>>

The BMJ has just published results of an epidemiological study in the UK suggesting at least one in 100 children have the disease (nearer 1 in 80 is likely).   There has been coverage today in the UK press and media including on BBC so subscribers to this list with access to BBC might catch it on the BBC 1 news tonight at 6am or 10pm GMT. See this link for the BBC report http://news.bbc.co.uk/1/hi/health/3461667.stm and this for the full BMJ article:
Undiagnosed coeliac disease at age seven: population based prospective birth cohort study, http://bmj.bmjjournals.com/cgi/content/full/328/7435/322
It ends withComments: 
"At age 7, 1% of children were IgA-EMA positive and likely therefore to have subclinical coeliac disease, though less than 0.1% were reported to be on a gluten-free diet. The prevalence of coeliac disease in these children is therefore comparable to that in UK adults.5 The benefit of early diagnosis of subclinical coeliac disease remains unproven, but long term follow up of this cohort may help to resolve this. If screening is worth while, it should be started in childhood..."
"Reported clinical features were similar to those in adults with coeliac disease identified by screening. Gastrointestinal symptoms were not prominent, and the excess in girls mirrors that seen in affected adults.  The most striking observation was that children with IgA-EMA were shorter by more than 0.76 standard deviation scores and lighter by 0.54 standard deviation scores than antibody negative children matched for date and place of birth. This equates to about 9 months' growth and weight gain in an average child around this age. These features were independent of gastrointestinal symptoms and anaemia and presumably unrelated to malabsorption."
This observation about size should help concerned parents in the UK in getting their children tested even when short stature is the only overt symptom.  Calls for screening all children for CD may follow.
Charlotte, Oxford, UK

*Support summarization of posts, reply to the SENDER not the CELIAC List*

ATOM RSS1 RSS2