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Carta M, 2003.  Recurrent brief depression in celiac disease, Jour
Psychosomatic Res 55:  573-574.
A letter to editor from study authors regarding RBD:

36% of celiac patients compared to 6.9% of 144 control patients were found
with RBD.  This association was stronger with RBD than major depression.
There was no significant difference between the RBD rates between men (33%)
and women (37%) but the association among women was found to be
statistically significant.

The heightened risks in CD patients were for the following mood disorders:
1) major depressive, 2) dysthymic disorders, 3) adjustment disorders, and 4)
panic disorders.

The authors hypothesized that the association bet. CD and mood disorders
might be explained by the following mechanisms:
1)  malabsorption of tryptophan leading to lower serotonin production
2)  autoimmunity:  cytokines (certain proteins produced by the body)


Laura Y.

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