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Kit Kellison <[log in to unmask]>
Reply To:
Kit Kellison <[log in to unmask]>
Date:
Wed, 22 Mar 2006 10:20:15 -0800
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<<Disclaimer: Verify this information before applying it to your situation.>>

A couple of years ago I read a study from a link provided by a lister that showed that things such as paprika, ibuprofen, NSAIDS and marathon running caused intestinal permeation.  I've tried googling it and went through all the March and April 2003 archives and haven't found in.  If Roy Jamron is still on the list, maybe he remembers it, maybe he posted the original link.  I had it saved but lost it when my harddrive crashed.  I should have backed it up, I know! Or at least put it in my yahoo briefcase where it would still be today.
   
  Any help accessing it would be welcome.
   
  In that vein, I'd like to recommend Synergy-Blackwell's free online service as a means of finding journal studies from many different specialties and even other disciplines (architecture, fine art, etc.)  I have no financial interest in this company, but it looks like a great start for integrating different areas of medical knowledge.  Maybe, someday, someone will propose a standard by which every possible symptom's manifestation has to be searched and consults made with the relevant specialists before treatment is introduced.  I'm thinking now of my refusal to take the suggestion of my rheumatologist to go on NSAIDS and Ibuprofen and other painkillers for fibromyalgia when I am having moderate to severe intestinal problems. He is totally unaware of any possible connection between the autoimmune process and leaky gut, he says.  Anyway~ as in all things: Caveat emptor!
   
  I was interested in the question posed in the WSJ article about the man who was supoosedly misdiagnosed with CD.  There are several possiblilities which come to mind given the limited information presented in the post, and presumably, the article.  
  1.) another gene (HLA DQ6?) 
  We've all read again and again that it is well known that in America, only 98% of celiacs have either of these genes, and that other geness have long been suspected as having some responsibility. (See Dr. Peter H.R. Green's excellent new book "Celiac Disease, A Hidden Epidemic" for a discussion of this issue)
  2% of the population is still a big number
  .
  2.) The second biopsy might have missed the bad patch, or it was healed.  I don't know how long this guy was gluten-free. It doesn't make any sense unless he was given a gluten challenge, to assume his diagnosis was wrong before doing sera tests and biospy.
   
  3.) The guy, after his gut was healed, may have been in remission OR
   
  4.) His gut wasn't damaged enough after whatever gluten challenge he is presently in to become symptomatic. 
   
  This article seems dangerously under-researched for its conclusion which could affect patient trust of diagosis and, therefore, diet compliance. Dr. Green, I believe, said that statistics reflecting compliance range anywhere between 20-80% of diagnosed celiacs. If anyone remembers a publication regarding the influence a doctor has on his patient's dietary compliance, I'd like to see that too.  My rheumatologist has a very dim view of the likelihood of dietary complinance.  He treats a lot of his fibromyalgia patients for IBS, he says.
   
  Kit in St. Lousi
   
   
   


Kit Kellison

Word of the Day for Thursday February 12, 2004

latitudinarian \lat-uh-too-din-AIR-ee-un; -tyoo-\, adjective:
Having  or  expressing broad and tolerant views, especially in religious matters.
noun:
1. A person who is broad-minded and tolerant; one who displays freedom in thinking, especially in religious matters.
2.  (Often  capitalized) A member of the Church of England, in the  time  of  Charles II, who adopted more liberal notions in respect  to  the  authority,  government, and doctrines of the church than generally prevailed.
		
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