<<Disclaimer: Verify this information before applying it to your situation.>>
Part 2: Do-It-Yourself Sorbitol H2 Testing
Roy S. Jamron
With the exception of lactulose and d-xylose, all sugars used in these
tests are cheap and readily available at supermarkets and health food
stores. Your body isn't going to know the difference between a fancy
expensive pharmaceutially labelled jar of sorbitol or a cheap one pound bag
of sorbitol used for baking. Below is a summary of sugar products using
Now Foods as an example:
Sorbitol - 1 lb $4.49
http://www.nowfoods.com/?action=itemdetail&item_id=4084
Lactose Milk Sugar - 1 lb $3.29
http://www.nowfoods.com/?action=itemdetail&item_id=4082
Fructose Fruit Sugar - 24 oz. $2.19
http://www.nowfoods.com/?action=itemdetail&item_id=3495
Dextrose (Glucose) - 2 lb. $3.29
http://www.nowfoods.com/?action=itemdetail&item_id=4079
Sucrose is available as common refined granulated cane or beet table sugar
which has a purity greater than 99%.
Lactulose syrup for bacterial overgrowth and intestinal transit time
testing is only available in the U.S. by prescription, but can readily be
obtained in Canada where no prescription is required.
D-Xylose (wood sugar) can be obtained from scientific or chemical supply
companies such as Fisher Scientific: https://www1.fishersci.com/index.jsp
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World J Gastroenterol 2004; 10(18): 2715-2718
Assessment of autonomic function in untreated adult coeliac disease
Giorgetti GM, Tursi A, Iani C, Arciprete F, Brandimarte G, Capria A,
Fontana L.
http://www.wjgnet.com/1007-9327/10/2715.asp
"Also sorbitol H2 breath test (H2-BT) was performed. All patients were
studied after an overnight fasting having been instructed to consume a meal
of rice and meat; they were also requested not to smoke on the morning of
the test day. End expiratory samples were collected before the patients
drank the test solution (5 g of sorbitol in 150 mL of tap water) and every
30 min for 4 h. Hydrogen concentrations in each collected sample were
measured with a breath-hydrogen analyzer (EC60 Gastrolyzer Breath Hydrogen
Monitor, Bedfont Scientific Ltd, Upchurch - Kent, England [U.K.]). An
increase in H2 concentration of at least 20 ppm over fasting baseline was
considered positive for sorbitol malabsorption."
Dig Liver Dis. 2002 Dec;34(12):846-50.
Sorbitol H2-breath test versus anti-endomysium antibodies to assess
histological recovery after gluten-free diet in coeliac disease.
Tursi A, Brandimarte G, Giorgetti GM
"As far as concerns sorbitol H2-Breath Test, maximal cut-off value (in ppm)
decreased progressively and parallel to histological recovery during follow-
up. Indeed, it decreased from a mean 63 ppm before diet to 35, 19 and 12
ppm, after 6, 12 and 18 months of gluten-free diet, with a statistical
difference being found before and after (p < 0.001). Likewise, the peak
value (in minutes) appeared progressively later during follow-up, parallel
to histological recovery. In fact, it appeared at a mean of 119 minutes
before gluten-free diet, while it appears at a mean of 164, 195 and 219
minutes after 6, 12 and 18 months on gluten-free diet."
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QuinTron MicroLyzers
http://www.quintron-usa.com/index.htm
Model CM2 MicroLyzer
http://www.quintron-usa.com/CM2MicroLyzer.htm
Med1 Online QuinTron MicroLyzer Price List
http://www.med1online.com/c-493-breath-analyzer.aspx
Breath Testing & Gastroenterology
http://www.quintron-usa.com/pdf_files/BreathTestsGastroenterology.pdf
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Micro Medical Micro H2
http://www.micromedical.co.uk/products/proddetail2.asp?spiro_id=34
Micro Direct
http://www.breathh2.com/microH2.asp
Micro Direct Order Form and Price List
http://www.breathh2.com/orderform.asp
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EC60 Gastrolyzer2 Breath Hydrogen Monitor - UK Website
http://www.gastrolyzer.com/
USA Website
http://www.bedfontusa.com/hydrogen.htm
USA Order Form and Price Sheet
http://www.bedfontusa.com/PDFs/Bedfont%20Order%20Form.pdf
Evaluation of the Accuracy of a Portable Device, Gastrolyzer EC60 Bedfont,
For Hydrogen (H2) Detection in Expired Air.
Di Stefano M, Missanelli A, Miceli E, Mazzocchi S, Corazza GR.
Gastroenterology Unit, IRCCS Policlinico S. Matteo, University of Pavia,
Pavia; Italy.
http://www.gastrolyzer.com/download/paper.pdf
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For further background information on the sorbitol H2 breath test see:
The Sorbitol H2-Breath Test - Part 1 & 2
http://maelstrom.stjohns.edu/CGI/wa.exe?A2=ind0506d&L=celiac&P=6276
http://maelstrom.stjohns.edu/CGI/wa.exe?A2=ind0506d&L=celiac&P=6398
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