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Subject:
From:
"Kendall D. Corbett" <[log in to unmask]>
Reply To:
Cerebral Palsy List <[log in to unmask]>
Date:
Fri, 27 Oct 2006 16:04:51 -0600
Content-Type:
text/plain
Parts/Attachments:
text/plain (240 lines)
Another interesting POV on the Michael J. Fox - Rush Limbaugh brouhaha
(I've always wanted to use that word!)  ;-{)}

http://www.newsday.com/news/nationworld/nation/ny-usads264948265oct26,0,6443351.story?coll=ny-uspolitics-headlines

Kendall

On 10/27/06, ken barber <[log in to unmask]> wrote:
> thanks for the articles. there are those that state
> just the oposite. i do not know which scienctist are
> right.
>
> --- "Kendall D. Corbett" <[log in to unmask]>
> wrote:
>
> > Article on use of embryonic stem cell use in
> > Parkinsons
> >
> > http://www.pnas.org/cgi/content/abstract/99/4/2344
> >
> > Another article:
> >
> > http://ask.lub.lu.se/archive/00016097/01/nm1064.pdf
> >
> > states that there is little evidence that other
> > types of stem cells
> > work as well as embryonic cells:
> >
> >  "Neurons with dopaminergic phenotype surviving
> > transplantation have
> > been generated in culture from mouse and monkey
> > embryonic stem cells
> > (ESCs) and from neural stem cells (NSC's) derived
> > from the fetal
> > rodent and human brain.  There is little evidence
> > that dopaminergic
> > neurons can be made from NSCs in adult brain or from
> > stem cells in
> > other tissues."
> >
> > (Page 2 of the PDF, near the bottom of the left
> > column.)
> >
> > Kendall
> >
> > On 10/27/06, Joshua Snyder <[log in to unmask]>
> > wrote:
> > > A while back, I remember a scientist stating that
> > such
> > > problems were likely with embryonic stem cells,
> > but
> > > not with adult (cord blood) stem cells.
> > >
> > > Two years ago, Miss Hwang Mi-soon was made to walk
> > for
> > > the first time after 19 years with adut stem cell
> > > therapy:
> > >
> > >
> >
> http://times.hankooki.com/lpage/tech/200412/kt2004120317543511780.htm
> > >
> > > The story was buried:
> > >
> > > http://www.lewrockwell.com/sardi/sardi58.html
> > >
> > > We have to ask, why the huge push (and funding)
> > for
> > > embryonic stem cell research from the same folks
> > who
> > > want an abortuary in every neighborhood? Why the
> > > elaborate ruse to divert us away from cord blood
> > stem
> > > cells?
> > >
> > > --- "Kendall D. Corbett"
> > <[log in to unmask]>
> > > wrote:
> > >
> > > > Ken and Kat,
> > > >
> > > > I also wonder what would have happened had the
> > study
> > > > used rat stem
> > > > cells rather than human stem cell implanted in
> > rats.
> > > >  A woman I worked
> > > > with had a kidney transplant several years back,
> > and
> > > > later developed a
> > > > tumor in that kidney and ureter.  I'm not saying
> > for
> > > > sure it was some
> > > > form of auto immune response, but I'd think the
> > > > likelihood of an
> > > > autoimmune elated cancer developing would be
> > higher
> > > > when cros-species
> > > > transplantation is performed.  I'm not
> > advocating
> > > > doing experimental
> > > > research on humans, but a check to see if tumors
> > > > develop in rats with
> > > > Parkinson's who are given rat stem cells would
> > seem
> > > > logical.
> > > >
> > > > Kendall
> > > >
> > > > On 10/27/06, Kathleen Salkin
> > <[log in to unmask]>
> > > > wrote:
> > > > > The study was truly inconclusive as they
> > killed
> > > > the test animals
> > > > > before any tumors formed.   So we don't know
> > if
> > > > the tumors would have
> > > > > been benign or malignant, or even if they
> > would
> > > > have formed.  Also,
> > > > > would this have been the result of short-term
> > > > treatment or long-
> > > > > term?  Too many questions to be really
> > conclusive.
> > > > >
> > > > > Kat
> > > > >
> > > > >
> > > > > On 27 Oct 2006, at 00:37, Kendall D. Corbett
> > > > wrote:
> > > > >
> > > > > Ken,
> > > > >
> > > > > Is this the link you were talking about?  If
> > so,
> > > > it does indicate an
> > > > > area where caution should be observed, but
> > since
> > > > there was improvement
> > > > > of the Parkinson's symptoms, I'd say it's too
> > > > early to abandon the
> > > > > research entirely, especially since even in
> > this
> > > > study, the results
> > > > > seem to be inconclusive.
> > > > >
> > > > > Kendall
> > > > >
> > > > >
> > http://today.reuters.com/news/articlenews.aspx?
> > > > >
> > > >
> > >
> >
> type=healthNews&storyID=2006-10-23T215819Z_01_TON379089_RTRUKOC_0_US-
> > > > >
> > STEM-CELLS.xml&WTmodLoc=NewsArt-C2-NextArticle-1
> > > > >
> > > > > Stem cells might cause brain tumors, study
> > finds
> > > > >
> > > > > WASHINGTON (Reuters) - Injecting human
> > embryonic
> > > > stem cells into the
> > > > > brains of Parkinson's disease patients may
> > cause
> > > > tumors to form, U.S.
> > > > > researchers reported on Sunday.
> > > > >
> > > > > Steven Goldman and colleagues at the
> > University of
> > > > Rochester Medical
> > > > > Center in New York said human stem cells
> > injected
> > > > into rat brains
> > > > > turned into cells that looked like early
> > tumors.
> > > > >
> > > > > Writing in the journal Nature Medicine, the
> > > > researchers said the
> > > > > transplants clearly helped the rats, but some
> > of
> > > > the cells started
> > > > > growing in a way that could eventually lead to
> > a
> > > > tumor.
> > > > >
> > > > > Various types of cell transplants are being
> > tried
> > > > to treat Parkinson's
> > > > > disease, caused when dopamine-releasing cells
> > die
> > > > in the brain.
> > > > >
> > > > > This key neurotransmitter, or message-carrying
> > > > chemical, is involved
> > > > > in movement and Parkinson's patients suffer
> > muscle
> > > > dysfunction that
> > > > > can often lead to paralysis. Drugs can slow
> > the
> > > > process for a while
> > > > > but there is no cure.
> > > > >
> > > > > The idea behind brain cell transplants is to
> > > > replace the dead cells.
> > > > > Stem cells are considered particularly
> > promising
> > > > as they can be
> > > > > directed to form the precise desired tissue
> > and do
> > > > not trigger an
> > > > > immune response.
> > > > >
> > > > > Goldman's team used human embryonic stem
> > cells.
> > > > Taken from days-old
> >
> === message truncated ===
>
>
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