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From:
ken barber <[log in to unmask]>
Reply To:
Cerebral Palsy List <[log in to unmask]>
Date:
Fri, 27 Oct 2006 12:04:21 -0700
Content-Type:
text/plain
Parts/Attachments:
text/plain (225 lines)
thanks for the articles. there are those that state
just the oposite. i do not know which scienctist are
right. 

--- "Kendall D. Corbett" <[log in to unmask]>
wrote:

> Article on use of embryonic stem cell use in
> Parkinsons
> 
> http://www.pnas.org/cgi/content/abstract/99/4/2344
> 
> Another article:
> 
> http://ask.lub.lu.se/archive/00016097/01/nm1064.pdf
> 
> states that there is little evidence that other
> types of stem cells
> work as well as embryonic cells:
> 
>  "Neurons with dopaminergic phenotype surviving
> transplantation have
> been generated in culture from mouse and monkey
> embryonic stem cells
> (ESCs) and from neural stem cells (NSC's) derived
> from the fetal
> rodent and human brain.  There is little evidence
> that dopaminergic
> neurons can be made from NSCs in adult brain or from
> stem cells in
> other tissues."
> 
> (Page 2 of the PDF, near the bottom of the left
> column.)
> 
> Kendall
> 
> On 10/27/06, Joshua Snyder <[log in to unmask]>
> wrote:
> > A while back, I remember a scientist stating that
> such
> > problems were likely with embryonic stem cells,
> but
> > not with adult (cord blood) stem cells.
> >
> > Two years ago, Miss Hwang Mi-soon was made to walk
> for
> > the first time after 19 years with adut stem cell
> > therapy:
> >
> >
>
http://times.hankooki.com/lpage/tech/200412/kt2004120317543511780.htm
> >
> > The story was buried:
> >
> > http://www.lewrockwell.com/sardi/sardi58.html
> >
> > We have to ask, why the huge push (and funding)
> for
> > embryonic stem cell research from the same folks
> who
> > want an abortuary in every neighborhood? Why the
> > elaborate ruse to divert us away from cord blood
> stem
> > cells?
> >
> > --- "Kendall D. Corbett"
> <[log in to unmask]>
> > wrote:
> >
> > > Ken and Kat,
> > >
> > > I also wonder what would have happened had the
> study
> > > used rat stem
> > > cells rather than human stem cell implanted in
> rats.
> > >  A woman I worked
> > > with had a kidney transplant several years back,
> and
> > > later developed a
> > > tumor in that kidney and ureter.  I'm not saying
> for
> > > sure it was some
> > > form of auto immune response, but I'd think the
> > > likelihood of an
> > > autoimmune elated cancer developing would be
> higher
> > > when cros-species
> > > transplantation is performed.  I'm not
> advocating
> > > doing experimental
> > > research on humans, but a check to see if tumors
> > > develop in rats with
> > > Parkinson's who are given rat stem cells would
> seem
> > > logical.
> > >
> > > Kendall
> > >
> > > On 10/27/06, Kathleen Salkin
> <[log in to unmask]>
> > > wrote:
> > > > The study was truly inconclusive as they
> killed
> > > the test animals
> > > > before any tumors formed.   So we don't know
> if
> > > the tumors would have
> > > > been benign or malignant, or even if they
> would
> > > have formed.  Also,
> > > > would this have been the result of short-term
> > > treatment or long-
> > > > term?  Too many questions to be really
> conclusive.
> > > >
> > > > Kat
> > > >
> > > >
> > > > On 27 Oct 2006, at 00:37, Kendall D. Corbett
> > > wrote:
> > > >
> > > > Ken,
> > > >
> > > > Is this the link you were talking about?  If
> so,
> > > it does indicate an
> > > > area where caution should be observed, but
> since
> > > there was improvement
> > > > of the Parkinson's symptoms, I'd say it's too
> > > early to abandon the
> > > > research entirely, especially since even in
> this
> > > study, the results
> > > > seem to be inconclusive.
> > > >
> > > > Kendall
> > > >
> > > >
> http://today.reuters.com/news/articlenews.aspx?
> > > >
> > >
> >
>
type=healthNews&storyID=2006-10-23T215819Z_01_TON379089_RTRUKOC_0_US-
> > > >
> STEM-CELLS.xml&WTmodLoc=NewsArt-C2-NextArticle-1
> > > >
> > > > Stem cells might cause brain tumors, study
> finds
> > > >
> > > > WASHINGTON (Reuters) - Injecting human
> embryonic
> > > stem cells into the
> > > > brains of Parkinson's disease patients may
> cause
> > > tumors to form, U.S.
> > > > researchers reported on Sunday.
> > > >
> > > > Steven Goldman and colleagues at the
> University of
> > > Rochester Medical
> > > > Center in New York said human stem cells
> injected
> > > into rat brains
> > > > turned into cells that looked like early
> tumors.
> > > >
> > > > Writing in the journal Nature Medicine, the
> > > researchers said the
> > > > transplants clearly helped the rats, but some
> of
> > > the cells started
> > > > growing in a way that could eventually lead to
> a
> > > tumor.
> > > >
> > > > Various types of cell transplants are being
> tried
> > > to treat Parkinson's
> > > > disease, caused when dopamine-releasing cells
> die
> > > in the brain.
> > > >
> > > > This key neurotransmitter, or message-carrying
> > > chemical, is involved
> > > > in movement and Parkinson's patients suffer
> muscle
> > > dysfunction that
> > > > can often lead to paralysis. Drugs can slow
> the
> > > process for a while
> > > > but there is no cure.
> > > >
> > > > The idea behind brain cell transplants is to
> > > replace the dead cells.
> > > > Stem cells are considered particularly
> promising
> > > as they can be
> > > > directed to form the precise desired tissue
> and do
> > > not trigger an
> > > > immune response.
> > > >
> > > > Goldman's team used human embryonic stem
> cells.
> > > Taken from days-old
> 
=== message truncated ===


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