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Date:
Mon, 22 Mar 1999 11:59:10 EST
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<<Disclaimer: Verify this information before applying it to your situation.>>

I am posting the following information for the Columbia Genome Center at
Columbia University College of Physicians and Surgeons, New York, NY.  The
Center is looking for families who have more than one member affected with
Celiac Disease, to participate in a genetic research study.  Information about
the study is included below.  All inquiries should be made to the Genetic
Coordinator, Michele Pallai, at (203) 438-3582 or email: [log in to unmask]

Regards,
Sue Goldstein
White Plains, NY

==========================

Genetic Research Study of Celiac Disease

The Columbia Genome Center
Columbia University College of Physicians and Surgeons
New York, New York

Searching for the Celiac Disease Gene

The Columbia Genome Center is sponsoring a research program at the Columbia
University College of Physicians and Surgeons to identify the gene responsible
for Celiac Disease.  Professor of Genetics and Development, T. Conrad Gilliam,
renowned for mapping the genes responsible for Wilson disease and spinal
muscular atrophy, is leading the investigation.  In addition to his own
research staff, Professor Gilliam has access to all of the resources of the
Columbia Genome Center for ancillary support of this project.

Role of Families with Celiac Disease

The key to this type of study is the participation of families in which there
are at least two family members affected with Celiac Disease.  Participation
of unaffected, as well as affected members may be needed.  Those individuals
who consent to participate will be asked to provide a sample of blood (20cc)
for DNA analysis and give permission for release of their diagnostic records
for review by Dr. Peter Green, Clinical Professor of Medicine.  Blood
collection can be done through a physician's office or a blood drawing
laboratory.  Participants will be provided with a blood drawing kit. The
project will cover the costs of drawing the sample and its shipment.  Guidance
will be provided by the Genetic Coordinator, Michele Pallai.

Who can participate in the study?

Anyone representing a family with two family members affected with Celiac
Disease can participate.

Why should I participate?

The involvement of multiple families will best enable the identification of
the genetic cause of Celiac Disease. It is anticipated that this
identification will lead to earlier diagnosis and effective treatment.

What will I have to do?

You will need to donate a sample of blood and release your diagnostic records.
Any incurred costs will be reimbursed.

All interested individuals should contact the Genetic Coordinator, Michele
Pallai, at (203) 438-3582 or email: [log in to unmask]

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