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Fri, 10 Jul 1998 09:48:19 EDT
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<<Disclaimer: Verify this information before applying it to your situation.>>

In response to Bev Wahl's question about the correct genetic markers for
celiac disease:

The genetic markers associated with celiac disease are

HLA DQalpha *0501
HLA DQbeta *0201

More than 90% of patients with CD have these markers. Negative tests for these
markers in conjunction with negative serum antibody tests suggest an absence
of CD. However, positive tests for the genetic markers do not necessarily mean
that the patient has celiac disease.

In conclusion, genetic markers can be used as a test to exclude celiac disease
as a diagnosis.

Vijay Kumar, PhD.
IMMCO Diagnostics, Inc.

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