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The following was posted to the autism mailing list/newsgroup:
 
On Thu, 19 Oct 1995, Toril Myrtveit <[log in to unmask]> wrote:
 
>I just went to a week-end cooking course (for g/c-free foods), where I
>learned that most people with casein intolerance didn't tolerate soy either.
>(no soy-milk, no soy-margarine, no soy sauce,...) This was all new to me.
>Supposedly, the soy-intolerance is due to the caseinates being similar in
>soy and cow-milk. Sounds wacko to me, and there was no medical experts there
>to explain why this should be so.
 
Being curious, I sent this to Dr. Reichelt, and this is his reply:
 
Date:    Sat, 21 Oct 1995 09:21:04 +0100
From:    [log in to unmask] (Kalle Reichelt)
Subject: Soy intolerance
 
Hi.
The evidence for this is very dubious. Sometimes when children are allergic
(IgE mediated) to milk their antibodies may cross react with soy bean
proteins. <Therefore if we are not satisfied with the progress of children
on gluten & casein free diet, soy protein has been removed too. I do not
find any definite effect of this.)
Exorphins have not been found from soy-proteins. The only bioactive
peptides found so far are antioxidant peptides from Soybean
beta-Conglycinin (1), and an immunomodulating peptide (2).
All proteins do give rise to peptides during uptake from the gut, and if
not broken down or otherwise increased they may inhibit the break down of
other dietary and also endogenous peptides. The reason for this has been
extensively discussed (3), and is due to peptides generally being good
peptidase inhibitors.
Therefore increasing the intake of peptidases (not proteinases) in
enterosoluble capsules like those from papaya would be a good idea.
Preliminary data look promising.
 
References:
1: Chen H.M et al (1995) Structural analysis of antioxidative peptides
from Soybean Beta-Conglycinin. j Agricult and Food Chem 43: 574-578.
2: Yamauchi F and Suetsuna K (1993) Immunological effects of dietary
peptide derived from soybean protein. J Nutr Biochem 4: 450-457.
3: LaBella FL et al (1985) Administration of peptides inhibit the
degradation of enodgenous peptides. The dilemma of distinguishing direct
from indirect effects. Peptides 6: 645-660.
 
All the best                            Cheers
 
                                        TINY
 
K. Reichelt
Pediatric Research Institute
N-0027 Oslo, Norway
Tel: +47 22 86 90 45
Fax: +47 22 86 91 17
E-mail: [log in to unmask]