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Subject:
From:
Kemp Randolph <[log in to unmask]>
Date:
Mon, 29 Jan 1996 10:13:24 -0500
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<<Disclaimer: Verify this information before applying it to your situation.>>
 
On Jan 28, 1996 11:36:39, 'Rebecca Markle <[log in to unmask]>' wrote:
 
>A long while ago, there was a question (from me?) about the
>difference between celiac disease and gluten intolerance.
>because I don't think everyone is aware that
>there are two distinct conditions that respond to a
>gluten-free/dairy-free diet.
>
>CELIAC DISEASE                  GlUTEN INTOLERANCE
>
>Symptoms: Diarrhea and weight         Gray Area.  Linked with migraines,
>loss prevalent, ranges to con-        dyslexia, hayfever, excema.
>stipation.                            Not sure about precise bowel
>symptoms.
 
The difference is that between two immune related reactions, allergy and
intolerance. I asked the question of the technical difference between the
two some time ago and got no response. It's not based on overt symptoms,
that's for sure. We're also not talking about the difference between latent
celiac disease and overt weight-loss, apple belly CD. You can be allergic
and intolerant of the same substance or food. In the case of milk, it's
lactose(milk carbohydrate) intolerance and milk protein allergy
 
My non-professional stab at the difference between intolerance and allergy
then. Both can lead to intestinal damage. There's a table in Marsh's book
showing that --page 155 , figure 6.13. Type 3 damage ("flat destuctive" )
can occur from milk, soya, egg.... as well as celiac disease.
 
The  reaction to an intolerance seems to be that the substance is not
digested. The immune part of the response involves only the circulating
immunoglobins IgA, maybe IgG and related immune cells, receptors.
 
The immune reaction to an allergy involves IgE. The substance may still be
digested, but there may be allergic responses elsewhere outside the gut.
 
 Apple belly CD is an intolerance. THe problems elsewhere in the body,
except for cancer, are related to nutritional deficiencies. The link to
other autoimmune diseases is statistical genetics when two (or more) genes
for each of two conditions are close together.
 
                              Kemp Randolph
                              Long Island
                              [log in to unmask]

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