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There was one study looking at family histories of CD patients and an
increased prevalence of colon cancer cases was hinted at.
Intestinal cancer in the setting of celiac disease may actually be
lymphoma or adenocarcinoma of the small intestine both directly? related
to CD.  A causal relationship to colon cancer is speculative.  Holmes
group in Britain di not reveal an increased incif=dence of colon cancer
in their patients.
Their is no ready explanation for the incidence in Ireland.
One could speculate that Ireland's subsistence on the potatoe for
200years might have allowed celiacs to flourish unencumbered by gluten
and the reintroduction of gluten lead to the disease.
Other possibilities migt include early infant feeding practices or a
limited genetic stock. Their are equally high areas of incidence in other
places, parts of Sweden, Italy, and Israel.
Joe murray