The Echo line of Alexa enabled products stand alone. There is a support 
app though called the Alexa Ap for smart phones which permits one to 
tweak some features of the Echo and Alexa products. There is also a web 
based app for this purpose, but most blind people find it really 
difficult to use.

As far as which is best? Depends on your desired use. The Echo Dot is 
by far the cheapest, and has all the capabilities, but a poor speaker. 
However, it does have both blue tooth and a mini jack output so you can 
tie it into a good stereo system and it sound great. If all you need is 
a controller for Alexa enabled appliences, and you don't plan to play 
music on it, the Dot is fine.

The Echo 2 is a good sounding stand alone speaker with plenty of 
volume. It too can be connected to a stereo or blue tooth device though 
if you want.

The Echo Plus has a built in smart device controller, so you won't need 
a hub for lights, locks or thermostadts.

The Echo Show has a screen, is comparatively expensive, and of no use 
in my book for a blind person.

The Echo Spot is basically a clock radio concept, and not worth its 
extra costs.

The Fire TV also has Alexa, and is fully accessible. It can control 
video streaming, but can also provide all the Alexa music and command 
services. It must be tied to a television though to function as it uses 
the TV speakers.

I have three Echos. Two Dots, both tied to stereo systems, one in my 
living room, one in my music studio, and then a regular Echo in my 
bedroom. They can all function together, or separately. I also have a 
Fire TV. I am totally hooked on the Echo and Alexa products. I shop 
through them all the time. I love the music service, and the games and 
look up functions are very useful. I have not tried them as appliance 
controllers as yet.
HTH
Bill


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