Hi Rachel,
Nope, it is a jaws issue, and it has been since word 2007.
Every time you press alt f4 to save, it crashes.
So, what you will have to do is, turn jaws off, and press windows key 
enter and Narrator will come on, then, you press alt f4 and you will be 
able to save your document.
Harry

On 8/13/2016 10:58 PM, Rachel Graff wrote:
> I just got a new computer today, so I'm running Windows 10, JAWS 17, 
> and Word 2016.  Every time I go to save a Word file with JAWS running, 
> it causes Word to crash.  When JAWS is not running, I can save a file 
> just fine.  Does JAWS not work well with Word 2016?
>
> Thanks in advance for any help you can provide.
>
> Rachel
>
>
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