"Efficacy trials are a test of whether an intervention does more good
than harm when delivered under optimal conditions. Program
implementers are usually highly trained professionals, and the
conditions are closely monitored to ensure that targeted participants
receive a maximal dose of the intervention. Effectiveness trials, on
the other hand, test whether an intervention does more good than harm
under real-world conditions."
Small efficacy trials of an indicated model substance abuse program
conducted by developers provide insufficient evidence of effectiveness.
Hallfors et all, Am J Public Health. 2006:2254-2259.
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