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-----Original Message-----
From: Charles Grashow <[log in to unmask]>
Sender: Paleolithic Eating Support List <[log in to unmask]>
Date: Sat, 16 Apr 2011 20:17:45
To: <[log in to unmask]>
Reply-To: Paleolithic Eating Support List <[log in to unmask]>
Subject: Re: Making the rounds
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http://advan.physiology.org/content/28/3/105.full
Understanding lipoproteins as transporters of cholesterol and other
lipids
Abstract
A clear picture of lipoprotein metabolism is essential for
understanding the pathophysiology of atherosclerosis. Many students
are taught that low-density lipoprotein-cholesterol is "bad" and
high-density lipoprotein-cholesterol is "good." This misconception
leads to students thinking that lipoproteins are types of
cholesterol rather than transporters of lipid. Describing
lipoproteins as particles that are composed of lipid and protein
and illustrating the variation in particle density that is
determined by the constantly changing lipid and protein composition
clarifies the metabolic pathway and physiological function of
lipoproteins as lipid transporters. Such a description will also
suggest the critical role played by apolipoproteins in lipid
transport. The clarification of lipoproteins as particles that
change density will help students understand the nomenclature used
to classify lipoproteins as well.
On Sat, 16 Apr 2011 18:09:45 -0400 Keith Thomas <[log in to unmask]>
wrote:
>Subject: Making the rounds
>From: David Harrison <[log in to unmask]>
>Date: Fri, 15 Apr 2011 09:45:
>
>Good article making the rounds.
>http://www.nytimes.com/2011/04/17/magazine/mag-17Sugar-t.html
>http://www.youtube.com/watch?v=dBnniua6-oM
>
>Taubes is a great story teller and knows where to weave in
>explanations of unfamiliar concepts.
>
>The whole story is scary. Despite all the accumulating knowledge,
>few scientists are willing to break ranks. Could it be something
>to do with the financial incentives for drugs to deal with
>diabetes, heart disease, obesity etc., and for the processed food
>industry to continue using sugar. Neither the pharmaceutical
>industry nor the processed food industry are concerned about human
>health; their main purpose is the generation of profit. Not also
>the way Keys shut down Yudkin and those who supported him by
>ridicule - that's not the way were are told science is supposed to
>work.
>
>On this point, I saw recently (but sadly, did not keep) research
>into why people purchase and eat the main foods in their diet.
>"Health" did not rate among the top reasons, even among people who
>declared they wanted to eat healthily. The main reasons included
>taste/mouth feel, price, minimal/no preparation, status (the image
>promoted by advertising), proximity (availability close to time
>and place desired), familiarity.
>
>Back to Taubes. He didn't take the opportunity to question the
>terms "HDL cholesterol - the good cholesterol" and "LDL
>cholesterol - the bad cholesterol", when both are lipoproteins,
>not sterols at all, let alone cholesterol. Nor is one good and the
>other bad: both are essential to a normally-functioning healthy
>human metabolism and, indeed, are made by our bodies for wholly
>beneficial reasons.
>
>Keith
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