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People with a positive celiac blood tests but no positive biopsy usually are diagnosed as "potential" celiac patients and may or may not be advised to follow a gluten-free diet. 

This study finds that such people shared the same  biochemical markers  as confirmed celiacs and differed significantly from healthy individuals. 

The researchers concluded: "Our results demonstrate that metabolic alterations may precede the development of small intestinal villous atrophy and provide a further rationale for early institution of gluten-free diet in patients with potential celiac disease, as recently suggested by prospective clinical studies,". 


read the whole article in: http://www.medicalnewstoday.com/articles/211738.php

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