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Tue, 3 Jun 1997 22:55:50 -0400 |
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>> PST deficiency--namely, the effect this deficiency would
>> have on the permeability of the intestinal lining.
>
>Very interesting ... There is a reprint you should request from your
>univeristy library, here's the citation:
> Debas HT, Mulvihill SJ. Neuroendorine design of the gut. Am J
Surgery
> 1991; 161:243-249.
>
>This is a good start to understanding the gut and serotonin. Admittedly
>well written for surgeons <TIC>!
>
>This serotonin thing is cool. Did you know that migraine sufferers can
>abort an episode by forcing themselves to vomit? Apparently, vomiting
>and other GI contractions cause a release of gut serotonin which enters
>the brain and somehow arrests the headache. This mechanism may be
>related to vasomotor properties of serotonin on the cerebral vessels.
Amazing! I didn't know that!
>I did a paperchase search last night and obtained 33 citations on PST.
>Am loking over them closely. Did find a reference to modulation to PST
>by quercetin the bioflavanoid from the rutin family. Quercetin
>downregulates PST. Will keep you abreast.
Quercetin also prevents degranulation of the mast cells, which therefore
cannot release histamine. Perhaps it acts by this mechanism. I take it for
allergies.
##############################################################
The two major neurotransmitters involved in preventing
depression are serotonin and norepinephrine. You can manipulate
these by providing their amino acid precursors.
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