Geoff:

You've raised an interesting item: do consumed glycatinated substances
contribute to AGEs in vivo?

One powerful intervention for preventing, possibly reversing AGEs is
interval strength training; moreover, that method results in upwards of 25%
greater carnosine stores assuming supplementation with beta-alanine.
Supplemental carnosine is likewise effective.

Recently published studies indicate cataracts result from AGEs, while
topical administration of acetyl-l-carnosine has been shown to arrest
further cataract development, and in some cases reverse it. Best bet is to
eliminate sugars from the diet altogether.

On Tue, Jan 19, 2010 at 4:29 PM, Geoffrey Purcell
<[log in to unmask]>wrote:

> I wouldn't be surprised if cooked palaeo had a small effect. After all,
> many highly processed foods contribute heavily to inflammation, not just
> cooked foods in general.
>
>
>
> As for cooking meat rare, that does reduce the amounts of AGEs, and
> therefore the symptoms, to some extent. It's certainly not as effective as
> raw, but it's still a major improvement on eating meats well-done.
>
> Some palaeos who don't identify themselves as rawpalaeo as such, don't seem
> to mind only searing the meats on the outside for a short period but leaving
> the meats largely raw on the inside.
>
>
>
> Geoff
>
>
>
>
>
>
>
>
> > Date: Tue, 19 Jan 2010 14:05:12 -0500
> > From: [log in to unmask]
> > Subject: Re: Arthritis question...
> > To: [log in to unmask]
> >
> > Thanks for all the links, Geoff. Very interesting (and a bit
> > disheartening) reading! Suggesting raw fruits & veggies is easy enough
> > but I don't think raw meat is going to fly. Would it be of any benefit
> > to cook the meat as rare as palatable, not allowing it to brown?
> > Wouldn't that reduce the AGE's?
> > I just turned 48 yesterday so I can see what's coming. I eat most of my
> > veggies raw, all fruits raw, but raw meat has been the stickler for me.
> > I used to be a well-done girl, then went to med-well, then med. and now
> > I am down to med.-rare. Do you feel that while not perfect, I am on the
> > right track? This I might be able to push on my picky non-paleo sisters.
> >
> > Stevie
> >
> > On 1/19/2010 4:21 AM, Geoffrey Purcell wrote:
> > > A cooked, palaeolithic diet wouldn't be any good for getting rid of
> osteoarthritis. This is because it's been pointed out that modern
> hunter-gatherers on traditional diets also get osteoarthritis, even if they
> eat a cooked palaeo diet:-
> > >
> > >
> > >
> > >
> > > http://en.wikipedia.org/wiki/Paleolithic_diet#Observational_studies
> > >
> > >
> > >
> > > Given that heat-created toxins derived from cooked foods, specifically
> advanced glycation end products(aka "AGEs"), are routinely linked to general
> age-related inflammation, and the number of studies done on the connection
> between AGEs and osteoarthritis:-
> > >
> > >
> > >
> > > http://www.ncbi.nlm.nih.gov/pubmed/11822407
> > >
> > >
> > >
> > > http://arthritis-research.com/content/6/S3/78
> > >
> > >
> > >
> > >
> http://www3.interscience.wiley.com/journal/107642826/abstract?CRETRY=1&SRETRY=0
> > >
> > >
> > >
> > >
> > >
> > > http://www.febsletters.org/article/S0014-5793(07)00368-7/abstract<http://www.febsletters.org/article/S0014-5793%2807%2900368-7/abstract>
> > >
> > >
> > >
> > > going rawpalaeo(ie raw meat, raw fruit/raw veg) would be more likely to
> work than any other method.
> > >
> > >
> > >
> > > Geoff
> > >
> > >
> > >
> > >
> > >
> > >
> > >> Date: Mon, 18 Jan 2010 16:19:46 -0500
> > >> From: [log in to unmask]
> > >> Subject: Arthritis question...
> > >> To: [log in to unmask]
> > >>
> > >> Hello everyone. This may be sort of off topic and I apologize in
> advance
> > >> if it is. I have read that paleo eating can help rheumatoid arthritis,
> > >> but haven't really found anything saying it's of benefit to
> > >> osteoarthritis--the wear and tear on joints as we age. Three of my
> > >> sisters have osteoarthritis and I've been trying to find info to help
> > >> them alleviate pain/inflammation and possibly to prevent further
> > >> deterioration of the joint.
> > >>
> > >> I'd appreciate any links, suggestions and/or personal experiences of
> > >> what may help.
> > >>
> > >> Thanks
> > >> Stevie
> > >>
> > >
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