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Eur J Gastroenterol Hepatol. 2007 Nov;19(11):1026-30.
Cystic lymphangioma of the mesentery and hyposplenism in celiac disease.
Miele L, Pierconti F, Forgione A, Vero V, Cammarota G, Molinari F, Masselli G,
Capristo E, Martini M, Larocca LM, Civello IM, Gasbarrini G, Grieco A.
Departments of aInternal Medicine bHuman Pathology cRadiology dSurgery,
Catholic University of Sacred Heart, Roma, Italy.
Celiac disease is characterized by intestinal inflammation and mucosal atrophy
that improves on a gluten-free diet. Delayed diagnosis can result in diet-
refractory disease known as refractory sprue, which is linked to other disorders
(intestinal lymphoma, ulcerative jejunoileitis, mesenteric lymph-node
cavitation, collagenous sprue, malignancy) and carries a poor prognosis. Here
we report the case of a young woman diagnosed with Marsh stage 3C celiac
disease with intestinal occlusion due to intra-abdominal cystic lymphangioma
mimicking mesenteric lymph-node cavitation, and hyposplenism.
Despite a number of prognostically negative features, the disease has been
managed successfully for the past 2 years with a gluten-free diet. The
pathogenesis, prognosis and therapeutic implications are discussed.
PMID: 18049176 [PubMed - in process]
Rosalie (NJ)
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