Cooley, Brad wrote:
> I have been meaning to research this more thoroughly since Geoffrey keeps
> making this point re AGEs and cooked meat. I understand that the damage
> from AGEs is from glycation occuring within the body due to high blood glucose
> levels, not from dietary consumption. I did find a reference that ~ 30% of
> AGEs consumed pass through the gut into the bloodstream, but am still
> skeptical whether this would have a negative effect on a heatlhy person (ie,
> the internal environment mitigates any potential damage).
>
> I suspect this is more raw propaganda. Unless you cook meat at a high
> temperature (how high I wonder?) with sugar, I do not think that AGEs can
> form. I know nothing about ALEs.
I recall an article on this in the Life Extension Foundation Magazine
and when looking for an URL. The temperature they recommend not to
exceed is 250 degrees F. However, water boils at 212 degrees F so that
might be the real magic number. The article also gave some
recommendations for eating out and some supplements that counteract AGEs
and ALEs.
Guard Your Precious Proteins Against Premature Aging
http://www.lef.org/magazine/mag2008/apr2008_Guard-Your-Proteins-Against-Premature-Aging_01.htm
Some quotes:
"The result is the formation of toxic substances known as AGEs—advanced
glycation end products—and ALEs—advanced lipoxidation end products."
"Glycotoxin levels increase dramatically in people who have elevated
blood glucose levels because these noxious substances thrive in
high-glucose environments. Thus, glycotoxins are especially prevalent in
individuals who have metabolic syndrome, predia-betes, or diabetes.
Sites in the body that are especially susceptible to the accumulation of
glycotoxins include the renal glomerulus (in the kidney), the retina
(the membrane at the back of the eye that helps you see), and important
blood vessels like the coronary arteries (the arteries that supply blood
to the heart). We also know that glycotoxins play a significant role in
causing chronic diseases that are associated with underlying
inflammation, such as heart disease and neuropathy."
"A key factor in the formation of food-derived glycotoxins is
temperature. Foods high in protein and fat (such as animal products like
beef, pork, poultry, fish, seafood, and lamb) as well as foods high in
fructose that are cooked, heated, or processed at high temperatures are
loaded with glycotoxins. High-temperature cooking methods should be used
sparingly—certainly not every day and only a few times a week if
possible. Instead, preparing food at temperatures less than 250°F
minimizes the formation of dietary glycotoxins. Such methods use liquids
and lower cooking temperatures and include poaching, steaming, braising,
stewing, and slow cooking (as in a crockpot cooker)."
"Be on the lookout for foods that are broiled, barbecued, grilled,
fried, or oven roasted—these cooking methods use high temperatures and
dry cooking conditions, which generate high levels of dietary
glycotoxins. Here’s a quick comparison of different cooking methods and
the resulting glycotoxin content of some common foods."
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