on 20/9/03 2:17 PM, [log in to unmask] at [log in to unmask] wrote:

> Hello.  Can anyone tell me if Soy products are not recommended if someone is
> hypothyroid, and on medication?  I seem to remember seeing that somewhere.  A
> friend stated that med. dr. from Mayo Clinic told her to take Soy...it would
> help to regulate her thyroid; as well as her meds.  Or something like that...
~~~~~~~~~~

Not recommended.  Shame on Mayo Clinic. There's lots in our archives about
soy.  NNF (Nutrition News Focus) has written about Mayo:

QUOTE
"A report in the November 2000 issue of the Mayo Clinic Proceedings
concludes that there is insufficient evidence to draw definite conclusions
for use of soy isoflavones as an alternative to estrogen for hormone
replacement in postmenopausal women.
http://www.mayo.edu/proceedings/2000/nov/7511sc1.pdf

HERE'S WHAT YOU NEED TO KNOW:  The authors of the Mayo Clinic report find no
compelling evidence for the effectiveness of soy isoflavones on any
condition for which they are touted.  They also point out that there are no
data on adverse effects in humans, but there are in animals (mostly
reproductive problems in females). None of the claims on packages except
that soy protein lowers serum cholesterol has  been evaluated or approved by
any government agency."
END QUOTE

And my files are full of articles such as the one below:

=================================================
NEW RESEARCH LOOKS AT ANTI-THYROID EFFECTS OF SOY AND
ITS ISOFLAVONES
=================================================

One of the world's leading soy researchers, Dr. Daniel Doerge, is lead
author on a research review that was recently published. The study looked at
the evidence in both people and animals that soy has anti-thyroid effects.

There were a number of interesting findings:

*  In animal studies, a diet heavy in soy was able to produce a severe
hypothyroid state characterized by decreased T4, increased TSH and enlarged
thyroid - but only when the animals were also iodine deficient.

*  In other animal studies, only whole soy - but not isoflavones alone -
were sufficient to produce a hypothyroid condition, and again, when the
animals were also iodine deficient

*  Soy-induced goiter, elevated TSH levels, and other hypothyroid indicators
can occur in humans in the absence of iodine deficiency.

*  There is evidence that soy consumption may adversely affect the course of
autoimmune thyroid disease in women.

*  Iodine deficiency is an increasing concern among Americans, because of
reduction in use of iodized salt as a treatment for high blood pressure.
Iodine deficiency may, in conjunction with soy consumption, be a combination
that can produce a hypothyroid condition in humans, and this warrants
further study.

*  Because of the connections between soy isoflavone ability to stimulate
certain immune function, promote formation of antigens, and worsen
autoimmune disease, further study of the use of soy formula in children is
warranted.

Source: Doerge, Daniel. R., Chang, Hebron, C.
"Review: Inactivation of thyroid peroxidase by soy isoflavones, in vitro and
in vivo," Journal of Chromatolography B, 777 (2002) 269-279


-- Joan McPhee, MH, WT
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