<<Disclaimer:  Verify this information before applying it to your situation.>>

The reference to the use of permeability in the diagnosis of celiac
disease is interesting.  However it is important to put it's usefulness
into context.  It detects increased intestinal permeability which is seen
in most untreated celiac patients.  However other diseases frequently
give rise to the same increase in permeability.  Hence I feel that the
utility of the test needs to be put in the context of the clinical
question.

Is a family member at risk of having CD also?

How is someones CD doing on a GFD?

These questions above may be answered by measuring permeability.
The question " does this patient have celiac disease?" is not answered by
detecting increased permeability.

Biopsy remains the standard.

Gliadin antibodiess ( esp IgG) can be seen in other diseasees.

Endomysial antibodies seem to more reliable than gliadin and rarely occur
in oter diseases( Note : this conclusion is based on our experince in
Iowa and published series from research labs in europe>  We do not know
how good( reliable ) this test will be in general usage, as more and more
labs start doing it. Joe Murray Iowa