C-PALSY Archives

Cerebral Palsy List

C-PALSY@LISTSERV.ICORS.ORG

Options: Use Forum View

Use Monospaced Font
Show Text Part by Default
Show All Mail Headers

Message: [<< First] [< Prev] [Next >] [Last >>]
Topic: [<< First] [< Prev] [Next >] [Last >>]
Author: [<< First] [< Prev] [Next >] [Last >>]

Print Reply
Subject:
From:
ken barber <[log in to unmask]>
Reply To:
Cerebral Palsy List <[log in to unmask]>
Date:
Fri, 27 Oct 2006 10:35:10 -0700
Content-Type:
text/plain
Parts/Attachments:
text/plain (237 lines)
you are right as one negative does not mean it it time
to abandon the research as there have been so many
positives. 

oh, in looking over even the positives i find these
warnings that once injected into the blood stream,
there is no control over where they can end up going
and that there could be problems if there were
undiscovered tumors already. 

i read one overall positive report that had a
paragraph way down in the report that a full 1/3 of
the injections had the cells ending up other than
where they were wanted and there were problems with
invasive tumors. but it was still overall a positive
report. 

--- Kathleen Salkin <[log in to unmask]> wrote:

> The study was truly inconclusive as they killed the
> test animals  
> before any tumors formed.   So we don't know if the
> tumors would have  
> been benign or malignant, or even if they would have
> formed.  Also,  
> would this have been the result of short-term
> treatment or long- 
> term?  Too many questions to be really conclusive.
> 
> Kat
> 
> 
> On 27 Oct 2006, at 00:37, Kendall D. Corbett wrote:
> 
> Ken,
> 
> Is this the link you were talking about?  If so, it
> does indicate an
> area where caution should be observed, but since
> there was improvement
> of the Parkinson's symptoms, I'd say it's too early
> to abandon the
> research entirely, especially since even in this
> study, the results
> seem to be inconclusive.
> 
> Kendall
> 
> http://today.reuters.com/news/articlenews.aspx? 
>
type=healthNews&storyID=2006-10-23T215819Z_01_TON379089_RTRUKOC_0_US-
> 
> STEM-CELLS.xml&WTmodLoc=NewsArt-C2-NextArticle-1
> 
> Stem cells might cause brain tumors, study finds
> 
> WASHINGTON (Reuters) - Injecting human embryonic
> stem cells into the
> brains of Parkinson's disease patients may cause
> tumors to form, U.S.
> researchers reported on Sunday.
> 
> Steven Goldman and colleagues at the University of
> Rochester Medical
> Center in New York said human stem cells injected
> into rat brains
> turned into cells that looked like early tumors.
> 
> Writing in the journal Nature Medicine, the
> researchers said the
> transplants clearly helped the rats, but some of the
> cells started
> growing in a way that could eventually lead to a
> tumor.
> 
> Various types of cell transplants are being tried to
> treat Parkinson's
> disease, caused when dopamine-releasing cells die in
> the brain.
> 
> This key neurotransmitter, or message-carrying
> chemical, is involved
> in movement and Parkinson's patients suffer muscle
> dysfunction that
> can often lead to paralysis. Drugs can slow the
> process for a while
> but there is no cure.
> 
> The idea behind brain cell transplants is to replace
> the dead cells.
> Stem cells are considered particularly promising as
> they can be
> directed to form the precise desired tissue and do
> not trigger an
> immune response.
> 
> Goldman's team used human embryonic stem cells.
> Taken from days-old
> embryos, these cells can form any kind of cell in
> the body. This batch
> had been cultured in substances aimed at making them
> become brain
> cells.
> 
> Previous groups have tried to coax stem cells into
> becoming
> dopamine-releasing cells.
> 
> Goldman's team apparently succeeded and transplanted
> them into the
> rats with an equivalent of Parkinson's damage. The
> animals did get
> better.
> 
> But the grafted cells started to show areas that no
> longer consisted
> of dopamine-releasing neurons, but of dividing cells
> that had the
> potential to give rise to tumors.
> 
> The researchers killed the animals before they could
> know for sure,
> and said any experiments in humans would have to be
> done very
> cautiously.
> 
> Scientists have long feared that human embryonic
> stem cells could turn
> into tumors, because of their pliability.
> 
> Opponents of embryonic stem cell research cite such
> threats. Many
> opponents, including President George W. Bush and
> some members of
> Congress, believe it is immoral to destroy human
> embryos to obtain
> their stem cells.
> 
> 
> (c) Reuters 2006. All Rights Reserved.
> 
> 
> 
> 
> 
> On 10/26/06, ken barber <[log in to unmask]> wrote:
> > in case you haven't heard one of the latest
> studies of
> > injecting stemcells into the brain show the
> propensity
> > of causing cancer and tumors. i wish i still had
> the
> > link.
> > we'll have to agree to disagree on mr. fox.
> >
> > --- "Kendall D. Corbett"
> <[log in to unmask]>
> > wrote:
> >
> > > Ken, since you've got your asbestos suit on,  I
> > > don't see it as Fox
> > > "playing the pity card," as you put it.  He's
> > > letting the public see
> > > the actual effects of the disease that he has. 
> Stem
> > > cell research has
> > > the potential to more effectively treat, if not
> cure
> > > this condition.
> > > Since your Mom (and my uncle ) died from
> > > Parkinson's, and a good
> > > friend is very seriously disabled by it, my
> thought
> > > is that research
> > > should be continued, especially since halting
> stem
> > > cell research is
> > > not going to halt abortion.  If a fetus is to be
> > > aborted anyway, which
> > > should always be the last option, what's so
> wrong
> > > with using some of
> > > the tissue that would otherwise be destroyed to
> > > improve the lives of
> > > others?
> > > Kendall
> > >
> > > On 10/25/06, ken barber <[log in to unmask]>
> wrote:
> > > > well, kat he has admitted to not taking his
> meds
> > > when > he makes public appearances that is to
> > > emphasise the > disease. he wrote it in his
> book.
> > > >
> > > > as much as this group does not like the
> "pitiful"
> > > card  played, i can not be >symathetic to the
> man
> > > playing the "pitiful card" in a polictical ad.
> > > >
> > > > rush limbaugh may be brash, caustic, and
> blunt,
> > > but he
> > > > is no idiot.
> > > >
> > > > i saw the ad and in my opinion, mr fox was off
> his
> > > > meds as he admits to doing at times. imho
> playing
> > > the
> > > > "pitiful card."  i resent it as my mom died
> with
> > > > parkingson's disease.
> > > >
> > > > go ahead, i have my asbestos suit on.
> > > >
> > > > --- Kathleen Salkin <[log in to unmask]>
> wrote:
> > > >
> > > > > Are you serious or do you have your tongue
> in
> 
=== message truncated ===


__________________________________________________
Do You Yahoo!?
Tired of spam?  Yahoo! Mail has the best spam protection around 
http://mail.yahoo.com 

-----------------------

To change your mail settings or leave the C-PALSY list, go here:

http://listserv.icors.org/SCRIPTS/WA-ICORS.EXE?SUBED1=c-palsy

ATOM RSS1 RSS2