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It's always nice to see medical science confirm the benefits of natural
therapies.

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Regular Intake of Yogurt Can Suppress H. pylori Infection
Yael Waknine
Medscape Medical News 2004. © 2004 Medscape

Sept. 2, 2004 - Ingestion of yogurt containing Lactobacillus acidophilus
(La5) and Bifidobacterium lactis (Bb12) significantly decreases urease
activity of Helicobacter pylori after six weeks, according to the results
of a placebo-controlled intervention study published in the September issue
of the American Journal of Clinical Nutrition.

Article (free registration with Medscape may be required):
http://www.medscape.com/viewarticle/488481

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Am J Clin Nutr 2004 80: 737-741

Effects of ingesting Lactobacillus- and Bifidobacterium-containing yogurt
in subjects with colonized Helicobacter pylori

Kuan-Yuan Wang, Shui-Nin Li, Chiang-Shin Liu, Daw-Shyong Perng, Yu-Chung
Su, Deng-Chyang Wu, Chang-Ming Jan, Chun-Huang Lai, Tsu-Nai Wang, and Wen-
Ming Wang

From the Department of Internal Medicine, Kaohsiung Municipal United
Hospital, Kaohsiung, Taiwan, Republic of China (K-YW and C-HL); the
Department of Biology (S-NL) and the School of Public Health (T-NW),
Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China; and the
Department of Pathology (C-SL) and the Department of Internal Medicine (D-
SP, Y-CS, D-CW, C-MJ, and W-MW), Kaohsiung Medical University Hospital,
Kaohsiung, Taiwan, Republic of China

Abstract:
http://intl.ajcn.org/cgi/content/abstract/80/3/737

Background: Evidence suggests that ingesting lactic acid bacteria exerts a
suppressive effect on Helicobacter pylori infection in both animals and
humans. Supplementing with Lactobacillus- and Bifidobacterium-containing
yogurt (AB-yogurt) was shown to improve the rates of eradication of H.
pylori in humans.

Objective: We administered AB-yogurt to subjects with asymptomatic H.
pylori to test whether the yogurt could inhibit H. pylori growth.

Design: The in vitro inhibition of H. pylori growth was determined by
inoculating Lactobacillus acidophilus La5 or Bifidobacterium lactis Bb12 on
plates that were inoculated with H. pylori. Assessment of the viability of
H. pylori was performed by the mixed culture method with La5 or Bb12. In an
intervention study, 59 adult volunteers infected with H. pylori were given
AB-yogurt (10**7 [10 million] colony-forming units of both La5 and Bb12/mL)
twice daily after a meal for 6 wk. Eleven subjects positive for H. pylori
infection were treated with milk placebo as control subjects. H. pylori
bacterial loads were determined with use of the 13C-urea breath test, which
was performed before and 4 and 8 wk after the start of AB-yogurt
supplementation.

Results: Bb12 exerted an in vitro inhibitory effect against H. pylori,
whereas La5 did not show an effect. Administration of AB-yogurt decreased
the urease activity of H. pylori after 6 wk of therapy (P < 0.0001).

Conclusion: Regular intake of yogurt containing Bb12 and La5 effectively
suppressed H. pylori infection in humans.

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