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From:
Thomas Schaefer <[log in to unmask]>
Reply To:
Thomas Schaefer <[log in to unmask]>
Date:
Mon, 9 Feb 2004 09:44:03 -0500
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<<Disclaimer: Verify this information before applying it to your situation.>>

I received 12 replies to my question about the relation between Celiac Disease and the subject condition. (also known as  EG.) 

 Some concerned patients who have been diagnosed with both:

1.  I am 46 years old and was diagnosed with Celiac Disease and Eosinophilic
Gastroenteritis.  My doctor prescribed a combination of Zyrtec and Zantac
because he explained that  EG is caused from the histamines that are in your
stomach.  The combination has worked wonders for me for 3 1/2 years.  I have
tried going off of the Zyrtec because of the high cost, but after about a
week I end up back in the same boat. 

2.  My 2 1/2 year old daughter has EG, and CD. I never heard of any correlation, other than both are non-IGE "allergies". A higher correlation to GERD (which she also has), perhaps...

3. I had been on a low carb diet for several years before I got diagnosed
gluten intolerant.  I felt so much better totally GF, that I foolishly
assumed that gluten was the root of all my GI problems.  I began eating
anyting in site as long as it was GF -- candy, baked goods, cookies,
cakes, sauces, etc.  After about 8 months I was sicker than I had ever
been in my life.  My GI specialist was at a loss as to how to help me so
he sent me to a naturopath in Seattle who specializes in such things.  I
was immediately diagnosed with allergic eosinophilic gastroenteritis. 
The ND did the following to help:
(1) Put me on the Specific Carbohydrate Diet (sugar free, starch free
diet)
(2) Got my GI specialist to prescribe oral cromalin sodium, a mast cell
stabalizer that enabled me to eat without pain
(3) Did allergy testing and took me off all reactive foods   
(4) Put me on Thorne Bio-Gest, a complete digestive enzyme formula
(5) Put me on a high quality probiotic (any that are kept in the
frigerator section of the health food stores)
(6) Put me on L-glutamine to help me heal my gut.

It took about six months to recover.  It's been about 2 years since I was
that sick.  I no longer need the cromalin sodium and L-gluteamine, but if
I skip the Bio-Gest, I get sick all over again.

4.  I also was diagnosed with Eosinophilic Gastroenteritis. Having found this on the biopsy, my doctor refused to do the blood tests for Celiac Disease! However, I react strongly to gluten, and follow a strict GF diet, which my doctor fortunately supports.

The international Celiac conference held in Baltimore a few years ago displayed several studies showing that those who have undiagnosed Celiac Disease are more likely to have other autoimmune conditions, including EG. The longer a person is undiagnosed and untreated (not on the GF diet), the more autoimmune conditions are likely to appear, and I have a bunch, including Langerhans Cell Histiocytosis, rosacea, and a mysterious form of arthritis.

I belong to a support list for adults with EG, and many members of this list also have CD or show signs of allergy to or intolerance of wheat! My doctor claims I'm in remission for EG now (although I don't consider 8 movements a day normal, nor 4-5 attacks of diarrhea a week, or occasional intense epigastric pain), but he keeps me on a low dose of Gastrocrom, which has helped me a lot. It is not useful for everyone; other treatments include prednisone. Avoidance of food allergens helps a lot, but these are hard to identify.  Here's the group's address:
http://health.groups.yahoo.com/group/Eosinophilgastro-Adult/

Ron Hoggan, co-author of Dangerous Grains, sent a relevant abstract: 

"Eosinophilic Gastroenteritis and Gluten-Sensitive Enteropathy in the Same
Patient   

Joseph H. Butterfield, M.D.; Joseph A. Murray, M.D.

From the Divisions of Allergic Diseases and Internal Medicine (J.H.B.) and
Gastroenterology and Hepatology and Internal Medicine (J.A.M.), Mayo Clinic,
Rochester, Minnesota, U.S.A.

JOURNAL OF CLINICAL GASTROENTEROLOGY 2002;34:552-553

We report the clinical and laboratory features of a 19-year-old man with
findings of both eosinophilic gastroenteritis and gluten-sensitive
enteropathy. Before the onset of clinical symptoms, the patient had received
a series of hepatitis B vaccinations but had not developed a measurable
antibody response or any allergic reaction. Radioallergosorbent test results
were positive to several foods, and the total serum immunoglobulin E (IgE)
level was elevated. Adherence to a gluten-free diet caused a normalization
in the endomysial antibody titer; however, the total serum IgE level
continued to increase, and the total eosinophil count remained elevated.
Symptoms of recurrent vomiting and abdominal pain necessitated prednisone
burst therapy. The simultaneous occurrence of eosinophilic gastroenteritis
and gluten-sensitive enteropathy is rare; therapy should be directed to each
disorder individually."

After reading these replies, I am once again reminded that nothing connected with Celiac Disease is crystal clear.  Some experts say that having both CD and EG is rare, but perhaps it occurs more often than they realize.

Thanks to those who responded.

*Support summarization of posts, reply to the SENDER not the Celiac List*

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