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Thu, 18 May 1995 09:04:17 -0400 |
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<<Disclaimer: Verify this information before applying it to your situation.>>
James Lyles <[log in to unmask] wrote on 17 May concerning someone
experiencing "neurological problems: unsteady gait, weakness of hands and
limbs, and muscle spasms."
The following abstract from Medline may be relevant:
MEDLINE(R) (c) format only 1995 Knight-Ridder Info. All rts. reserv.
09277252 95207252
[Celiac disease in adults revealed by sensory-motor neuropathy]
Maladie coeliaque de l'adulte revelee par une neuropathie sensitivo-motrice.
Viader F; Chapon F; Dao T; Rivrain Y; Lechevalier B
Service de Neurologie, CHRU de Caen.
Presse Med (FRANCE) Jan 28 1995, 24 (4) p222-4, ISSN 0755-4982
Journal Code: PMT
Languages: FRENCH Summary Languages: ENGLISH
Document type: JOURNAL ARTICLE English Abstract
JOURNAL ANNOUNCEMENT: 9506
Subfile: INDEX MEDICUS
Central or peripheral nervous system complications are occasionally
observed in adult patients with celiac disease. Several mechanisms have
been proposed including vitamin deficiency, vascular inflammation and a
direct effect of gluten intolerance. Typical nerve fiber damage due to
demyelinization has been suggested. We observed a 65-year old woman with a
right peroneal nerve palsy superimposed on a diffuse peripheral neuropathy
who was found to have folic acid deficiency which in turn led to the
diagnosis of adult celiac disease. Electrophysiological and histological
studies demonstrated a predominantly demyelinating peripheral neuropathy
which responded first to parenteral folic acid supplementation and second
to a gluten-free diet. The mechanisms of peripheral nerve damage in adult
celiac disease are briefly discussed and the possible role of folic acid
deficiency is emphasized.
Tags: Case Report; Female; Human
Descriptors:*Celiac Disease--Complications--CO; *Peripheral Nervous
System Diseases--Etiology--ET; Aged; Celiac Disease--Diagnosis--DI;
Demyelinating Diseases--Etiology--ET; Electrophysiology; Folic Acid
Deficiency--Complications--CO
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