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Subject:
From:
Greg De Guzman <[log in to unmask]>
Reply To:
Thyroid Discussion Group <[log in to unmask]>
Date:
Mon, 10 Feb 2003 09:49:25 +0800
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----- Original Message -----
From: "Edward Reisman" <[log in to unmask]>
>
> However, is there a good scientific explanation why that is so?  My guess
is
> that the TSH measures what's in the bloodstream, but not what's getting to
> the cells; also, it does not tell you about any resistance to thyroid
hormone
> or whether one's T4 is being converted in sufficient quantity to T3.

You are right. TSH is a measure of how much quantified stimulation the
thyroid is getting from the pituitary assuming there are no other factors
causing oversecretion (like growths). All these tests are just estimates for
the substances involved. For thyroid assays, the main source of disparity
lies in purity of samples (a big factor) and the interpretation. As we a all
know the norms used are just statistical samples from a given Lab. If my
memory serves me right, the way the TSH and the Hormone Levels must be
correlated is by a "Set Point" for a particular individual. If the TSH vs.
Hormone Level is graphed, there is a point at which the person feels
optimally normal, and, sliding either way as the points move. I do not have
it handy, but I've come accross some information about the magnitude of TSH
movements vs. Free Hormone Levels-- something like 1:6.

To quote Barnes, BO, Hypothyroidism: The Unsuspected Illness.. -- on the use
of Basal Body Temperature

<quote>
Apparently some physicians had reservations about a test which permit
patients to arrive at their own dignoses. Perhaps some had had reservations
because the test involved no fee. <end quote>

Greg




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