Hi Deb and everyone,
Narrow therapeutic window basically means there is a very fine line between
a proper (therapeutic) dose and an excessive dose which can lead to serious
side effects/problems. In drugs with narrow therapeutic windows, it is more
difficult to achieve correct dosing, and close monitoring is necessary
(particularly in elderly people or those with impaired liver and/or kidney
function).

Hope this helps,
Susan A


>On Mon, 18 Jun 2001, Sharon Johnson wrote:
>
>> Any narrow therapeutic window drug, though listed with certain
>> concentrations of the active principles, depend on the manufacturer.  That
>> is why on Thyroid (and anticoagulation- - warfarin, Coumadin) medicine
>> inserts it states that one should not switch brands or change the generic
>> brand.
>
You wrote:
>I wasn't able to find out what "narrow therapeutic window drug" means.
 >Any help?
>
>Deb
>

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