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Subject:
From:
Joan McPhee <[log in to unmask]>
Reply To:
Thyroid Discussion Group <[log in to unmask]>
Date:
Tue, 22 Jul 2003 11:10:08 -0600
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on 12/6/03 1:39 PM, Skipper Beers at [log in to unmask] wrote:

> I'm not sure what "conjugated" DHEA means.
~~~~~~~~~~~~~

Hope this helps, Skipper:

A conjugated hormone is one in which the hormone is linked to some other
molecule such as sulfates, acetates, carbohydrates (complex sugars).    An
example is estrone linked to a sulfate (sulfur and oxygen), i.e. estrone
sulfate.  Once in this linked or caged form the hormone is no longer active,
meaning that it cannot penetrate a cell, bind a hormone receptor, and carry
out its normal function at the gene level.  Conjugated hormones are a
storage form of hormone.  When taken orally the conjugated hormones are
broken down by the bacteria in the gastrointestinal tract and the active
hormone is released into the circulation.


-- Joan McPhee, MH, WT
   mailto:[log in to unmask] --

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