> I'm
> concerned about my husband because he has a different blood type for which
> the prescribed diet is to avoid red meat and eat tofu, fish, some poultry,
> beans, some grains and lots of fruits/veggies.

> He's about 50 pounds overweight.  I am probably
> going to feed him paleo and see how it affects his weight and cholesterol
> levels?
>
> I would appreciate any input, especially do you know of anyone who hasn't
> done well on a paleo diet?

I don't see how it could hurt to try that for a while, and see how it goes.
Everyone will respond differerently. Paleo is not necessarily low carb,
although it can be. It seems that if your husband wants to lose weight and
see how it goes, reduced carb paleo would be the way to go.

--Richard