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Thu, 21 Feb 2002 18:53:40 -0500 |
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<<Disclaimer: Verify this information before applying it to your situation.>>
The England Journal of Medicine (Vol. 346, No. 3, 1/17/02) cites the
following clinical presentations of Celiac Sprue:
Definite Associations:
Dermatitis Herpetiformis
IgA deficiency
Type 1 diabetes
Autoimmune thyroid disease
Sjogren's syndrome
Microscopic Colitis
Rheumatoid arthritis
Down's syndrome
IgA nephropathy
Possible associations:
Congenital heart disease
Recurrent pericarditis
Sarcoidosis
Cystic fibrosis
Fibrosing alveolitis
Lung cavities
Pulmonary hemosiderosis
Inflammatory bowel disease
Autoimmune hepatitis
Primary biliary cirrhosis
Addison's disease
Systemic lupus erythematosus
Vasculitis
Polymyositis
Myasthenia gravis
Schizophrenia
Complications:
Refractory sprue
Enteropathy associated T-cell lymphoma
Carcinoma of the oropharynx, esophagus, and small bowel
Ulcerative jejunoileitis
Collagenous sprue
Common Features:
Adults- Iron deficieny anemia, Diarrhea
Children- Diarrhea, Failure to thrive, Abdominal distention
Less Common Features:
General Features - Short Stature, delayed puberty
Gastrointestinal Features - Recurrent aphthous stomatitis, recurrent
abdominal pain, steatorrhea
Extraintestinal Features-
Folate-deficiency anemia
Osteopenia or osteoporosis
Dental-enamel hypoplasia
Vitamin K deficiency
Hypertransaminasemia
Thrombocytosis (hyposplenism)
Arthralgia or arthropathy
Polyneuropathy
Ataxia
Epilepsy (with or without cerebral calcification)
Infertility
Recurrent abortions
Anxiety and depression
Follicular keratosis
Alopecia
Regards, Laura
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