Exercise is widely recommended for diabetics as a means of increasing their
insulin sensitivity.  Virtually unknown it seems, from my search of the
web, including Medscape, is the possible loss of insulin receptors from
exercise that Art mentions in his posting on post-workout nutrition.  Wiley
and Femby in their book "Lights Out," discussed here in November, suggests
that "excessive exercise" *alone* may cause a loss of insulin receptors
over time.  While the authors do talk much about the dangers of high
carbohydrate diets, there is no explicit or any apparent contextual
qualification where this statement is made.

Can someone clarify this ambiguity?

By the way, hamiltonbook.com (or hamiltonbooks.com?) is selling hardcover
editions of "Lights Out" for $8.95.  You can also buy it indirectly through
half.com.  I'll search their bibliography for a relevant citation when I
get a hold of it.  (I skimmed it at a bookstore.)

Ming

On Thu, 1 Feb 2001 17:01:22 -0800, Arthur De Vany <[log in to unmask]> wrote:

>Yes, high GI meals after a work out do restore muscle glycogen, but the
insulin surge they cause interacts with the growth hormone released by the
work out to do bad things.  First, the GH makes you slightly insulin
resistant after a work out (this temporary resistance is the price you pay
for high insulin sensitivity for the following 18 hours after a high
intensity workout).  Putting a high glycemic meal into the blood stream at
that time causes insulin to be released which compounds the insulin
resistance induced by the high GH and may cause some loss of insulin
receptors over a long period of doing this repeatedly.
>
>Second, the GH keeps the fatty acids released by the stress hormones
during the work out from re-esterfying, which means the body can metabolize
fat efficiently in the post work out period.  That is why I walk or shoot
baskets after a work out and why one should do cardio after, not before a
workout.  That is the max period of fat burning.
>
>Third, take elevated free fatty acids in the blood stream and add insulin
along with a high glycemic meal and you have a classic situation that
affects adult onset diabetics: poor fatty acid metabolism, high blood
concentration of fatty acids and triglycerides, high circulating insulin,
and high blood glucose.  Why would you want to mimic diabetes?  Nothing
good comes of it and much damage over time.
>
>Fourth,  you want to drain the glycogen from your muscle.  Muscle that is
full of glycogen is not a good glucose sink.  Filled  up muscle makes you
insulin resistant and the whole cascade of events I described above unfolds
over a long period of time.  Emptying and filling the muscle through power
law variation creates the hormonal cascades that maintain insulin
sensitivity and high GH pulses.  That is where metabolic fitness comes from.
>
>By coincidence, I am doing a 5 day per week routine with no more than two
exercises, done hierarchically for three sets, followed by a few alactics.
>
>
>
>
>Arthur De Vany
>Professor
>Economics and Mathematical Behavioral Sciences
>University of California
>Irvine, CA 92697-5100
>949-824-5269
>http://aris.ss.uci.edu/econ/personnel/devany/devany.html