<<Disclaimer:  Verify this information before applying it to your situation.>>

If you don't have access to a medical library, one can usually get a
reprint by sending a request by mail to the authors which are listed
below in the more complete medline output.

1
UI  - 95054826
AU  - Miletic ID ; Miletic VD ; Sattely-Miller EA ; Schiffman SS
TI  - Identification of gliadin presence in pharmaceutical products.
LA  - Eng
MH  - Alcohol, Ethyl ; Blotting, Western ; *Drug Contamination ; Drugs/
      *CHEMISTRY ; Electrophoresis, Polyacrylamide Gel ; Enzyme-Linked
      Immunosorbent Assay ; Gliadin/*ANALYSIS ; Sodium Dodecyl Sulfate
      ; Solvents
RN  - 0 (Drugs) ; 0 (Solvents) ; 151-21-3 (Sodium Dodecyl Sulfate) ;
      64-17-5 (Alcohol, Ethyl) ; 9007-90-3 (Gliadin)
PT  - JOURNAL ARTICLE
AB  - Celiac disease is characterized by hypersensitivity to the
      alcohol-soluble wheat proteins called gliadins. Total avoidance
      of gliadin is the lifelong treatment for such patients. However,
      wheat gliadins are often present as impurities in industrial
      starch commonly used in the preparation of different
      pharmaceutical products. Therefore, some drugs might contain
      gliadin, which can be dangerous for sensitive patients if taken
      in large amounts or used permanently. The purpose of this study
      was to develop a sensitive, reliable assay that is specific for
      the detection of gliadins in pharmaceutical products. Gliadins
      were extracted here using sodium dodecyl sulfate rather than 70%
      ethyl alcohol, which has been the traditional solvent. This
      gliadin extract was utilized in a dot-blot assay that
      incorporated an antigliadin antibody developed in rabbit and
      labeled with peroxidase. 4-Chloro-1-naphthol was used as a
      peroxidase-specific substrate. Isolated wheat gliadin was used as
      the positive control. Dilution experiments showed that the lower
      level of sensitivity for the assay was in the range of 0.0045
      mg/ml of gliadin, which is a concentration level lower than that
      suggested for a gluten-free diet. The assay developed here
      revealed that 71.2% of 59 prescription and nonprescription drugs
      tested contained gliadin in the amount detected by our dot-blot
      assay. The prescription drugs tested were among the top 50 most
      frequently dispensed in U.S. community pharmacies. The
      nonprescription drugs were among those that constitute the
      largest sales in the United States. The results showed that the
      simple dot-blot assay developed here can be used for
      pharmaceutical testing performed either by hospital laboratories
      or by patients themselves.
AD  - Department of Psychiatry, Duke University, Durham, North Carolina
      27706.
SO  - J Pediatr Gastroenterol Nutr 1994 Jul;19(1):27-33