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Date: | Tue, 5 Sep 2000 09:36:52 -0400 |
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<<Disclaimer: Verify this information before applying it to your situation.>>
I may or may not have Celiac Disease. My blood tests were
inclusive (see below) and my biopsy was "consistent with" CD.
I have now been gluten free for 5 weeks; after 6 months I'll
have a second biopsy.
I would be much happier with gluten deprivation if the blood tests
offered stronger evidence of CD. Here were the results:
Gliadin IgA Ab: negative
Gliadin IgG Ab: strong positive
Reticulin Ab: negative
Endomysial AB IgA: negative
From Tom Ryan, "Tissue Transglutaminase Blood Tests",
THE SPRUE-NIK PRESS, Volume 9, Number 5, June-August 2000:
"IgA class anti-endomysial antibodies (AEA) are very specific,
occurring only in CD and DH. These antibodies are found in
approximately 80% of patients with DH and in essentially 100% of
patients with active CD. IgA endomysial antibodies are more sensitive
and specific than gliadin antibodies for diagnosis of CD."
I find the "essentially 100%" reference discouraging. My
gastro-enterologist discounts such statistics, but I'd
feel a lot more comfortable if my numbers were more
consistent with his diagnosis.
I'd appreciate any information which could shed light on my
diagnosis.
- Mark
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