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Mon, 6 Mar 2000 21:34:07 -0500 |
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<<Disclaimer: Verify this information before applying it to your situation.>>
OK - so I STILL didn't get all the fine points.
Am forwarding this response to you all, as Kemp more clearly explains
than I can. Also will send another person's response RE: testing sites
soon.
Ruth
> Ruth,
>
(first 7 lines from MY summary)
> >>To summarize as best I can:
> >>
> >> -the tTg (tissue transglutaminase) assay is a series of 4 tests
> >>
> >>(IgA autoantibodies, IgA + IgG gliadin autoantibodies, IgA endomysial
> >>autoantibodies, and IgA reticulin antoantibodies) which, when all
> >>evaluated together provide a 'probability of celiac disease with high
> >>probabilty.
(Kemp's reply)
> The set of four tests is usually called THE celiac antibody test. The
> tissue transglutaminase antibody test is a separate, more sensitive one.
> First reported in Nature Medicine July 1998. For diagnosis, there is hope
> it alone may be sufficient, so sufficient that it mean biopsy wasn't
> needed. For monitoring, it's thought to be more sensitive to gluten than
> the panel, allowing better monitoring of the diet.
>
> I thought one Maryland research study was aimed at the transglutaminase
> test: the only results I've received are for the celiac panel and I
> suspect results from the other will only be released after they have
> analyzed all the data. That is standard procedure in a research study.
>
> Kemp Randolph
> Long Island
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