<<Disclaimer: Verify this information before applying it to your situation.>> There was one study looking at family histories of CD patients and an increased prevalence of colon cancer cases was hinted at. Intestinal cancer in the setting of celiac disease may actually be lymphoma or adenocarcinoma of the small intestine both directly? related to CD. A causal relationship to colon cancer is speculative. Holmes group in Britain di not reveal an increased incif=dence of colon cancer in their patients. Their is no ready explanation for the incidence in Ireland. One could speculate that Ireland's subsistence on the potatoe for 200years might have allowed celiacs to flourish unencumbered by gluten and the reintroduction of gluten lead to the disease. Other possibilities migt include early infant feeding practices or a limited genetic stock. Their are equally high areas of incidence in other places, parts of Sweden, Italy, and Israel. Joe murray