It may work at some level, but you are much better off with Opus 9. 
There is no better full featured file manager, although it is so full 
featured, that the learning curve can be a bit daunting. However, 
Opus 9 is a marvelously coded multi threaded application that will 
reward you with time savings, and increased productivity once you 
spend the time learning how to fully use it.  http://www.gpsoft.com.au/

Rode
The NOSPIN Group
http://www.freepctech.com/rode/

>Has anyone tried using PowerDesk in VISTA with either good or bad
>results?
>(Their web site does not say anything about it working with VISTA.)
>Dean Kukral

      "Hold No Punches.." Rode brings you great shareware/freeware
        programs with his honest opinions in this weekly column.
                       http://freepctech.com/rode