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ABSTRACT:

Adult coeliac patients do tolerate large amounts of oats
Eur J Clin Nutr 2003 Jan;57(1):163-9     (ISSN: 0954-3007)
Storsrud S; Olsson M; Arvidsson Lenner R; Nilsson LA; Nilsson O; Kilander A
Department of Clinical Nutrition, Sahlgrenska University Hospital,
Gothenburg, Sweden.

OBJECTIVE: The aim of the present study was to investigate whether adult
patients with coeliac disease in remission could include large amounts of
oats in their daily gluten-free diet for an extended period of time without
adverse effects.

DESIGN, SUBJECTS AND METHODS: Twenty adult coeliac patients in remission
included large amounts of uncontaminated rolled oats in their daily diet
for a prolonged period. The examinations, performed four times during the
study period, included small bowel endoscopy with biopsies, blood samples
(nutritional status, serological analysis), height and body weight,
gastrointestinal symptoms and dietary records. Gastrointestinal symptoms
and diet were also investigated through unannounced telephone interviews
once a month during the study period.

RESULTS: No adverse effects of a large intake of oats were seen in small
bowel histology, serology nor in nutritional status in the 15 subjects who
completed the whole study period. Two of the subjects dropped out because
of gastrointestinal symptoms and three for non-medical reasons. The median
intake of oats was 93 g/day and the compliance to the oat diet was found to
be good. Examinations of the patients after drop-out did not show any
deterioration in small bowel histology or nutritional status nor raised
levels of antibodies.

CONCLUSION: Results from this study indicate that adult patients with
coeliac disease in remission can include large amounts of controlled wheat-
free rolled oats for an extended period of time without adverse effects.
SPONSORSHIP: This study was supported by Vardalstiftelsen,
Kommunalforbundet Vastra Gotaland, Stiftelsen Cerealia FoU, and the Swedish
Nutrition Foundation. Kungsornen AB supported the study with rolled oats.

European Journal of Clinical Nutrition (2003) 57, 163-169.

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