Thanks for the link Jean-Louis, I read it all. It has not changed my view that this is an important study and maybe at some point I'll have time to look at the original. The conclusion that some draw from the study is that cooked food is unnatural because of the leukocytosis. I think that is a strong possibility given that the effect is not seen with raw food. Just because eating 10% raw with your cooked can stop this effect is beside the point. The point for me is that the body is 'alarmed' by cooked food and not by raw. I agree that methods in the 20's/30's were probably not as good as today but are you suggesting that leukocytosis does not take place? I agree again that there is speculation but someone who is trying to find the optimum diet, for whatever reason needs to make choices given the available information. Should I wait until some scientist decides to repeat the experiments or should I use the speculative conclusions to try to puzzle out what the hell we humans should be eating - ideally. People who eat a raw food diet always report 'crashing' if cooked food is eaten after an extended period of raw. This represents the true reaction of the body to that foodstuff as regular consumption can mask it's true effect. Mike.