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Subject:
From:
David Ross <[log in to unmask]>
Reply To:
Raw Food Diet Support List <[log in to unmask]>
Date:
Sat, 24 Nov 2001 02:05:42 -0500
Content-Type:
text/plain
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text/plain (50 lines)
Thanks, Blake.

David

-----Original Message-----
From: Raw Food Diet Support List [mailto:[log in to unmask]]
On Behalf Of Blake Graham
Sent: Saturday, November 24, 2001 12:50 AM
To: [log in to unmask]
Subject: Re: B-12 Deficiency


From: http://216.118.123.225/health/b12.html

"Symptoms

Neurological Symptoms
Neurological symptoms are the biggest worry in B12 deficiency because
they can be irreversible. However, if caught early enough, they can be
reversed in many cases.

One theory of why nerve problems occur in B12 deficiency is from a lack
of methionine (from B12 not converting Hcy back into methionine) which
creates a lack of S-adenosylmethionine (SAM).35 SAM is required for the
production of phosphatidylcholine36 which is part of the myelin (the
fatty material that insulates many nerves). Phosphatidylcholine improves
nerve transmission.36

Another theory is that the altered nerve function of B12 deficiency is
possibly due to the body's inability to convert methylmalonyl-CoA (a 3
carbon molecule) to succinyl-CoA (a 4 carbon molecule). This inability
results in a build up of propionyl-CoA (a 3 carbon molecule). Fatty
acids are normally made by adding 2 carbons at a time to an even
numbered carbon molecule. In an overabundance of 3 carbon molecules,
large amounts of unusual 15-carbon and 17-carbon fatty acids could be
produced and incorporated into nerve sheets, causing altered nerve
function.103

Early Signs of B12 Deficiency
According to Crane et al.18 (1994, USA), the usual vegan patient has no
clinical symptoms or signs of inadequate B12. Early manifestations are
unusual fatigue, faulty digestion (no appetite or nausea) and loss of
menstruation. Other symptoms are nervousness, numbness and tingling of
the hands and feet, mild depression, striking behavioral changes,
paranoia, hyperactive reflexes, fever of unknown origin,18 frequent
upper respiratory infections,19 impotence, impaired memory,49
infertility,55 sore tongue, and diarrhea.60"

Blake

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