Do you actually need to use the serial port?  If not, you can disable it in your BIOS setup.  If you need it then you will have to change 3F8 to something else in your BIOS.

>Every time I boot up I get the following error message:  "I/O conflict
>3F8"
>
>I am running windows 98 SE with an
>
>I have checked under device manager.  No conflicts or problems are
>indicted and under "com ports" there  is no problem indicated and the
>comment is that there are no conflicts.
>
>I am using a Microsoft PS2 mouse.
>
>yet, when I attach a serial cable to com port 1 the mouse cursor is
>frozen!!
>
>As soon as I take the  cable out the mouse  again works.
>
>I am  aware that 3F8 is an address used by  com1.
>
>Can any kind person give a clue   as to how to rectify this conundrum?
>


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